Abstract Purpose of Review In this review, we describe molecular pathological epidemiology
(MPE) studies from around the world that have studied diet and/or lifestyle factors in relation …

Colorectal cancer (CRC) incidence changes with time and by variations in diet and lifestyle,
as evidenced historically by migrant studies and recently by extensive epidemiologic …

Background Both genetic and lifestyle factors play an etiologic role in colorectal cancer
(CRC). Objectives We evaluated potential gene–environment interactions in CRC risk …

Colorectal cancer (CRC) is a multifactorial disease resulting from lifestyle, genetic, and
environmental factors. There are hereditary and non-hereditary CRC types; however, the …

Colorectal cancer arises in individuals with acquired or inherited genetic predisposition who
are exposed to a range of risk factors. Many of these risk factors are associated with affluent …

Protective associations of fruits, vegetables, and fiber intake with colorectal cancer risk have
been shown in many, but not all epidemiologic studies. One possible reason for study …

366 Editorial| JNCI Vol. 102, Issue 6| March 17, 2010 can be a source of selection bias. The
potential for bias will vary by many factors that may affect availability of tissue. Molecular …

Purpose Individuals with family history of colorectal cancer are at higher risk of colorectal
cancer than the general population. Until now, guidelines for familial colorectal cancer risk …

Over the past few years, evidence has accumulated indicating that apart from genetic
alterations, epigenetic alterations, through eg aberrant promoter methylation, play a major …

Simple Summary This systematic review sifted through the exogenous dietary and lifestyle
risk factors associated with early-onset colorectal cancer, going through the putative …