Identifying metabolic alterations in newly diagnosed small cell lung cancer patients

P Shona, JB Hansen, RG Maltesen, WM Szejniuk… - 2021 - qspace.qu.edu.qa
BackgroundSmall cell lung cancer (SCLC) is a malignant disease with poor prognosis. At
the time of diagnosis most patients are already in a metastatic stage. Current diagnosis is …

[HTML][HTML] Identifying metabolic alterations in newly diagnosed small cell lung cancer patients

S Pedersen, JB Hansen, RG Maltesen, WM Szejniuk… - Metabolism Open, 2021 - Elsevier
Background Small cell lung cancer (SCLC) is a malignant disease with poor prognosis. At
the time of diagnosis most patients are already in a metastatic stage. Current diagnosis is …

[PDF][PDF] Metabolism Open

S Pedersen, JB Hansen, RG Maltesen, WM Szejniuk… - researchgate.net
Background: Small cell lung cancer (SCLC) is a malignant disease with poor prognosis. At
the time of diagnosis most patients are already in a metastatic stage. Current diagnosis is …

P2. 12-14 A Pilot Study of Serial Plasma Metabolomics in Small Cell Lung Cancer Patients

S Lee, K Pathak, M Mcgilvrey, K Mansfield… - Journal of Thoracic …, 2019 - jto.org
Background Small cell lung cancer (SCLC) is among the deadliest cancers. SCLC is
characterized by high proliferation and high turn-over metabolism. There are few results of …

Integrated omics and gene expression analysis identifies the loss of metabolite–Metabolite correlations in small cell lung cancer

L Yu, K Li, Z Xu, G Cui, X Zhang - OncoTargets and therapy, 2018 - Taylor & Francis
Background and objective Small cell lung cancer (SCLC) is the most aggressive type of lung
carcinoma with high metastatic potential and chemoresistance upon relapse. Cancer cells …

Untargeted metabolomics and lipidomics identified four subtypes of small cell lung cancer

C Zhang, X Shang, H Wang - Metabolomics, 2022 - Springer
Introduction Small cell lung cancer (SCLC) is a heterogeneous malignancy with dismal
prognosis. However, few studies have conducted on the metabolic heterogeneity in SCLC …

32P Untargeted metabolomics and lipidomics identified four subtypes of small cell lung cancer

C Zhang, X Shang, H Wang - Annals of Oncology, 2022 - annalsofoncology.org
Background Small cell lung cancer (SCLC) is a heterogeneous malignancy with dismal
prognosis. As molecular subtyping of SCLC with distinct genomic and transcriptional profiles …

Construction of a diagnostic model for small cell lung cancer combining metabolomics and integrated machine learning

X Shang, C Zhang, R Kong, C Zhao, H Wang - The Oncologist, 2024 - academic.oup.com
Background To date, no study has systematically explored the potential role of serum
metabolites and lipids in the diagnosis of small cell lung cancer (SCLC). Therefore, we …

1662P Comprehensive analysis of the metabolic enzymes in patients with small cell lung cancer using a large-scale targeted proteomics assay

G Toyokawa, M Kodama, N Haratake… - Annals of …, 2021 - annalsofoncology.org
Background Small cell lung cancer (SCLC) is a devastating subtype of lung cancer, and its
biological, clinical and genetic characteristics differ from those associated with non-small …

Comprehensive metabolic profiling and vulnerabilities to metabolic inhibitors among small cell lung cancer subtypes

KR Cargill, CM Gay, RJ Cardnell, YH Fan, Q Wang… - Cancer Research, 2020 - AACR
Small cell lung cancer (SCLC) is an aggressive neuroendocrine tumor that constitutes
approximately 14% of all lung cancers diagnosed in the United States. Despite recent …