Role of extracellular vesicles in lung diseases

L Zhou, H Luo, JW Lee - Chinese Medical Journal, 2022 - journals.lww.com
Extracellular vesicles (EVs) are anuclear particles composed of lipid bilayers that contain
nucleic acids, proteins, lipids, and organelles. EVs act as an important mediator of cell-to …

Extracellular vesicles in lung disease

H Kubo - Chest, 2018 - Elsevier
Accumulating evidence suggests that extracellular vesicles (EVs) play a role in the
pathogenesis of lung diseases. These vesicles include exosomes, ectosomes (ie …

[PDF][PDF] Role of extracellular vesicles in chronic lung disease

A Trappe, SC Donnelly, P McNally, JA Coppinger - Thorax, 2021 - thorax.bmj.com
To explore the role of extracellular vesicles (EVs) in chronic lung diseases. EVs are
emerging as mediators of intercellular communication and possible diagnostic markers of …

Extracellular vesicles as unique signaling messengers: role in lung diseases

Y Gao, JU Raj - Comprehensive Physiology, 2011 - Wiley Online Library
Extracellular vesicles (EVs) are lipid bilayer‐enclosed extracellular particles carrying rich
cargo such as proteins, lipids, and microRNAs with distinct characteristics of their parental …

[HTML][HTML] Stem-cell extracellular vesicles and lung repair

FF Cruz, PRM Rocco - Stem cell investigation, 2017 - ncbi.nlm.nih.gov
Four out of the ten leading causes of morbidity and mortality worldwide are lung diseases.
Despite advances in comprehending the pathophysiological mechanisms involved in these …

[HTML][HTML] Emerging role of extracellular vesicles in lung injury and inflammation

Z Lanyu, H Feilong - biomedicine & pharmacotherapy, 2019 - Elsevier
Lung injury and inflammation are common characterizes in many pulmonary diseases.
Alveolar epithelial cells, macrophages, pulmonary microvascular endothelial cells, and …

Extracellular vesicle biology in the pathogenesis of lung disease

SP Nana-Sinkam, M Acunzo, CM Croce… - American journal of …, 2017 - atsjournals.org
The human body is comprised of trillions of cells that are well organized into different
functional compartments, tissues, and organs. To maintain homeostasis, coordinated …

Clinical application of mesenchymal stem cell-derived extracellular vesicle-based therapeutics for inflammatory lung diseases

Y Fujita, T Kadota, J Araya, T Ochiya… - Journal of Clinical …, 2018 - mdpi.com
It is currently thought that extracellular vesicles (EVs), such as exosomes and microvesicles,
play an important autocrine/paracrine role in intercellular communication. EVs package …

Extracellular vesicles: novel communicators in lung diseases

A Mohan, S Agarwal, M Clauss, NS Britt… - Respiratory research, 2020 - Springer
The lung is the organ with the highest vascular density in the human body. It is therefore
perceivable that the endothelium of the lung contributes significantly to the circulation of …

Extracellular vesicles in lung microenvironment and pathogenesis

Y Fujita, N Kosaka, J Araya, K Kuwano… - Trends in molecular …, 2015 - cell.com
Increasing attention is being paid to the role of extracellular vesicles (EVs) in various lung
diseases. EVs are released by a variety of cells, including respiratory cells and immune …