Rapid developments in the field of molecular biology and gene technology resulted in
generation of many macromolecular drugs including peptides, proteins, polysaccharides …

Buccal formulations have been developed to allow prolonged localised therapy and
enhanced systemic delivery. The buccal mucosa, however, while avoiding first-pass effects …

Owing to the ease of the administration, the oral cavity is an attractive site for the delivery of
drugs. Through this route it is possible to realize mucosal (local effect) and transmucosal …

Within the oral mucosal cavity, the buccal region offers an attractive route of administration
for systemic drug delivery. The mucosa has a rich blood supply and it is relatively …

The buccal route offers an attractive alternative for systemic drug delivery of drugs because
of better patient compliance, ease of dosage form removal in emergencies, robustness, and …

The buccal region of the oral cavity is an attractive target for administration of the drug of
choice, particularly in overcoming deficiencies associated with the latter mode of …

Buccal drug delivery has gained significant attention and momentum since it offers
remarkable advantages. Over past few decades, buccal route for systemic drug delivery …

Since the early 1980s the concept of mucoadhesion has gained considerable interest in
pharmaceutical technology. The various advantages associated with these systems made …

Mucoadhesion can be defined as a state in which two components, of which one is of
biological origin, are held together for extended periods of time by the help of interfacial …

Modern pharmaceutical science has provided us with a wide range of substances to be
administered with a wide large variety of dosage forms. Local drug delivery systems have …