Diosgenin: An ingress towards solving puzzle for diabetes treatment

P Arya, P Kumar - Journal of Food Biochemistry, 2022 - Wiley Online Library
The consumption and composition of food in daily life predict our health in long run. The
relation of diabetes to sweets is quite popular. Diabetes hampers the glucose and insulin …

Fenugreek derived diosgenin as an emerging source for diabetic therapy

Y Tak, M Kaur, A Chitranashi, MK Samota… - Frontiers in …, 2024 - frontiersin.org
Diabetes is a chronic metabolic disease that endangers the entire body's tissues and
organs. Diabetes impairs glucose and insulin regulation in the human body by causing …

Diosgenin from Dioscorea bulbifera: Novel Hit for Treatment of Type II Diabetes Mellitus with Inhibitory Activity against α-Amylase and α-Glucosidase

S Ghosh, P More, A Derle, AB Patil, P Markad, A Asok… - PloS one, 2014 - journals.plos.org
Diabetes mellitus is a multifactorial metabolic disease characterized by post-prandial
hyperglycemia (PPHG). α-amylase and α-glucosidase inhibitors aim to explore novel …

[HTML][HTML] Diosgenin: Chemistry, extraction, quantification and health benefits

P Arya, M Munshi, P Kumar - Food Chemistry Advances, 2023 - Elsevier
The occurrence of natural bioactive compounds is increasingly involved with pharmaceutical
industries' exploring more source matrices. Diosgenin is a lot of delved bioactive compound …

[PDF][PDF] An update on the biological and pharmacological activities of diosgenin

JK Kim, SU Park - 2018 - 129.217.131.68
Trigonella, and Trillium, and many species of Dioscorea (Patel et al., 2013; Chen et al.,
2011). Fujii and Matsukawa first discovered diosgenin within Dioscorea tokoro Makino in …

[HTML][HTML] Dioscin: Therapeutic potential for diabetes and complications

H Gao, Z Wang, D Zhu, L Zhao, W Xiao - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Diabetes mellitus is a widespread metabolic disorder with increasing incidence worldwide,
posing a considerable threat to human health because of its complications. Therefore, cost …

Diosgenin reorganises hyperglycaemia and distorted tissue lipid profile in high‐fat diet–streptozotocin‐induced diabetic rats

PB Naidu, P Ponmurugan, MS Begum… - Journal of the …, 2015 - Wiley Online Library
BACKGROUND Diabetes is often connected with significant morbidity, mortality and also
has a pivotal role in the development of cardiovascular diseases. Diet intervention …

Diosgenin and its fenugreek based biological matrix affect insulin resistance and anabolic hormones in a rat based insulin resistance model

R Kiss, G Pesti-Asbóth, MM Szarvas… - BioMed research …, 2019 - Wiley Online Library
Fenugreek is known since ancient times as a traditional herbal medicine of its multiple
beneficial effects. Fenugreek's most studied and employed effect is its hypoglycemic …

The role of diosgenin in diabetes and diabetic complications

Q Gan, J Wang, J Hu, G Lou, H Xiong, C Peng… - The Journal of steroid …, 2020 - Elsevier
Diabetes mellitus is a chronic and common metabolic disease that seriously endangers
human health. Hyperglycemia and long-term metabolic disorders in diabetes will cause …

[HTML][HTML] Diosgenin, 4-hydroxyisoleucine, and fiber from fenugreek: mechanisms of actions and potential effects on metabolic syndrome

S Fuller, JM Stephens - Advances in Nutrition, 2015 - Elsevier
Metabolic syndrome and its complications continue to rise in prevalence and show no signs
of abating in the immediate future. Therefore, the search for effective treatments is a high …