Several psychiatric disorders—such as bipolar disorder, schizophrenia and autism—are
highly heritable, yet identifying their genetic basis has been challenging, with most …

Psychiatric genetics has made substantial progress in the last decade, providing new
insights into the genetic etiology of psychiatric disorders, and paving the way for precision …

The reputation of the field of psychiatric genetics has recently become tarnished in the view
of many human geneticists. Too many linked loci were claimed and withdrawn, too many …

For over a century, psychiatric disorders have been defined by expert opinion and clinical
observation. The modern DSM has relied on a consensus of experts to define categorical …

Psychiatric disorders are among the most intractable enigmas in medicine. In the past 5
years, there has been unprecedented progress on the genetics of many of these conditions …

Genome-wide association studies have identified hundreds of robust genetic associations
underlying psychiatric disorders and provided important biological insights into disease …

In this article, we review some of the data that contribute to our understanding of the genetic
architecture of psychiatric disorders. These include results from evolutionary modelling …

Background Despite evidence from twin and family studies for an important contribution of
genetic factors to both childhood and adult onset psychiatric disorders, identifying robustly …

Failure to obtain convincing results in psychiatric genetics can partly be attributed to the fact
that progress in molecular biology and genetic epidemiology has not been followed by an …

Psychiatric genetics has taught us a great deal about the nature of psychiatric disorders.
Traditional family, twin and adoption studies have demonstrated the substantial role of …