Doxycycline, a synthetically derived tetracycline, is a partially efficacious causal prophylactic
(liver stage of Plasmodium) drug and a slow acting blood schizontocidal agent highly …

Malaria, a parasite vector-borne disease, is one of the greatest health threats in tropical
regions, despite the availability of malaria chemoprophylaxis. The emergence and rapid …

Anti-malarial drug resistance to chloroquine and sulfadoxine–pyrimethamine has spread
from Southeast Asia to Africa. Furthermore, the recent emergence of resistance to …

The in vitro activities of doxycycline, chloroquine, quinine, amodiaquine, artemether,
pyrimethamine, and cycloguanil were evaluated against Plasmodium falciparum isolates …

Abstract 188 schoolchildren aged 10-15 living in a malaria endemic area along the Thai-
Burmese border were matched for age, splenomegaly, and weight and were then randomly …

The pharmacokinetics of oral doxycycline administered at 200 mg every 24 h were
investigated in 17 patients recovering from severe Plasmodium falciparum malaria. The data …

Azithromycin prevents malaria in animal models and early clinical trials. We determined the
prophylactic efficacy of three antibiotic regimens given for 10 weeks (azithromycin, 250 mg …

Background: Mefloquine and doxycycline are the two drugs recommended for prophylaxis of
malaria for visitors to areas where Plasmodium falciparum is resistant to chloroquine …

New drugs are needed for preventing drug-resistant Plasmodium falciparum malaria. The
prophylactic efficacy of azithromycin against P. falciparum in malaria-immune Kenyans was …

A double blind study of daily doxycycline (100 mg) vs. weekly mefloquine (250 mg) was
performed on United States soldiers training in Thailand to assess the effect of doxycycline …