Delivery of short chain fatty acid butyrate to overcome Fusobacterium nucleatum-induced chemoresistance

L Chen, R Zhao, Z Kang, Z Cao, N Liu, J Shen… - Journal of Controlled …, 2023 - Elsevier
The gut microbiota is closely associated with the progression of colorectal cancer (CRC) in
which Fusobacterium nucleatum (F. nucleatum) was found to induce cancer resistance to …

Sodium New Houttuyfonate Inhibits Cancer-Promoting Fusobacterium nucleatum (Fn) to Reduce Colorectal Cancer Progression

F Jia, Q Yu, L Zhao, Y Shen, H Guo, F He - Cancers, 2022 - mdpi.com
Simple Summary Colorectal cancer (CRC) is the third most common malignancy and the
second most deadly cancer worldwide. Recent studies have uncovered the close …

[HTML][HTML] Berberine may rescue Fusobacterium nucleatum-induced colorectal tumorigenesis by modulating the tumor microenvironment

YN Yu, TC Yu, HJ Zhao, TT Sun, HM Chen, HY Chen… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Background Accumulating evidence links colorectal cancer (CRC) with the intestinal
microbiota. However, the disturbance of intestinal microbiota and the role of Fusobacterium …

[HTML][HTML] Drugs, bugs, and cancer: Fusobacterium nucleatum promotes chemoresistance in colorectal cancer

A Ramos, MT Hemann - Cell, 2017 - cell.com
The tumor microenvironment has recently been shown to play decisive roles in
chemotherapeutic response. In this issue of Cell, Yu et al. add to these findings by …

[HTML][HTML] Fusobacterium nucleatum promotes colon cancer progression by changing the mucosal microbiota and colon transcriptome in a mouse model

N Wu, YQ Feng, N Lyu, D Wang, WD Yu… - World journal of …, 2022 - ncbi.nlm.nih.gov
BACKGROUND Fusobacterium nucleatum (F. nucleatum) has long been known to cause
opportunistic infections and has recently been implicated in colorectal cancer (CRC), which …

Fusobacterium nucleatum promotes colorectal cancer cells adhesion to endothelial cells and facilitates extravasation and metastasis by inducing ALPK1/NF-κB …

Y Zhang, L Zhang, S Zheng, M Li, C Xu, D Jia, Y Qi… - Gut …, 2022 - Taylor & Francis
Metastasis is the leading cause of death for colorectal cancer (CRC) patients, and the
spreading tumor cells adhesion to endothelial cells is a critical step for extravasation and …

Fusobacterium nucleatum host-cell binding and invasion induces IL-8 and CXCL1 secretion that drives colorectal cancer cell migration

MA Casasanta, CC Yoo, B Udayasuryan… - Science …, 2020 - science.org
Fusobacterium nucleatum is implicated in accelerating colorectal cancer (CRC) and is found
within metastatic CRC cells in patient biopsies. Here, we found that bacterial invasion of …

Vanillin Derivatives Reverse Fusobacterium nucleatum-Induced Proliferation and Migration of Colorectal Cancer Through E-Cadherin/β-Catenin Pathway

Z Zhou, Y Wang, R Ji, D Zhang, C Ma, W Ma… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) is a common clinical malignant tumor and closely related to
intestinal microbiome disorders. Especially, Fusobacterium nucleatum (F. nucleatum) is one …

Fusobacterium nucleatum Promotes Colorectal Cancer Cell to Acquire Stem Cell‐Like Features by Manipulating Lipid Droplet‐Mediated Numb Degradation

H Liu, J Du, S Chao, S Li, H Cai, H Zhang… - Advanced …, 2022 - Wiley Online Library
Fusobacterium nucleatum is a critical microbe that contributes to colorectal cancer
progression and chemoresistance. However, whether and how F. nucleatum regulates …

Fusobacterium nucleatum Acts as a Pro-carcinogenic Bacterium in Colorectal Cancer: From Association to Causality

S Wang, Y Liu, J Li, L Zhao, W Yan, B Lin… - Frontiers in Cell and …, 2021 - frontiersin.org
Colorectal cancer (CRC) is a common cancer worldwide with complex etiology.
Fusobacterium nucleatum (F. nucleatum), an oral symbiotic bacterium, has been linked with …