Herein, a doxorubicin-loaded carbon-based drug delivery system, denoted as PC-DOX,
composed of pH-responsive imine bond was developed for the tumor-targeted treatment. PC …

Aim: Doxorubicin-induced cardiotoxicity limited its clinical utilization in oncology. In this
study, Dox was entrapped into PEG-PLGA Nanoparticles, cardiotoxicity of Dox or PEG-PLGA …

The present study investigates the effects of the antioxidant and anticancer properties of
CoQ10-NPs on the efficacy and toxicity of Dox. Cell culture experiments revealed a …

Background and objective Targeted drug delivery of nanoparticles decorated with site-
specific recognition ligands is of considerable interest to minimize cytotoxicity of …

In this study, a highly effective transmembrane delivery vehicle based on PEGylated
oxidized mesoporous carbon nanosphere (oMCN@ PEG) was successfully fabricated in a …

A PEG-based, folate mediated, active tumor targeting drug delivery system using DOX-hyd-
PEG-FA nanoparticles (NPs) were prepared. DOX-hyd-PEG-FA NPs showed a significantly …

To bypass the biological barriers during the drug delivery process, it is desirable to develop
smart nanoparticles (NPs) with flexible physical and chemical properties. In this study, a …

Doxorubicin is an extensively prescribed antineoplastic agent. It is also known for adverse
effects, among which cardiotoxicity tops the list. The possible mechanism underlying …

The emergence of nanocarriers solves the problems of antitumor drugs such as non‐
targeting, huge side effects, etc., and has been widely used in tumor therapy. Some kinds of …

Doxorubicin (DOX) is a widely used chemotherapeutic drug to treat a range of cancers.
However, its unfavorable effects, particularly the cardiotoxicity and the induction of multidrug …