Iron–sulfur clusters (Fe–S) are one of the most ancient, ubiquitous and versatile classes of
metal cofactors found in nature. Proteins that contain Fe–S clusters constitute one of the …

Abstract Iron–sulfur (Fe–S) clusters are inorganic cofactors that are ubiquitous and essential.
Due to their chemical versatility, Fe–S clusters are implicated in a wide range of protein …

Mitochondria are the key organelles of Fe–S cluster synthesis. They contain the enzyme
cysteine desulfurase, a scaffold protein, iron and electron donors, and specific chaperons all …

Iron–sulfur clusters are ubiquitous inorganic co-factors that contribute to a wide range of cell
pathways including the maintenance of DNA integrity, regulation of gene expression and …

Iron–sulfur clusters are multifaceted iron‐containing cofactors coordinated and utilized by
numerous proteins in nearly all biological systems. Fe–S‐cluster‐containing proteins help …

Work during the past 14 years has shown that mitochondria are the primary site for the
biosynthesis of iron–sulfur (Fe/S) clusters. In fact, it is this process that renders mitochondria …

Iron–sulfur (Fe–S) clusters are ubiquitous co-factors of proteins that play an important role in
metabolism, electron-transfer and regulation of gene expression. In eukaryotes mitochondria …

Abstract Iron-Sulfur (Fe-S) clusters are essential for life, as they are widely utilized in nearly
every biochemical pathway. When bound to proteins, Fe-S clusters assist in catalysis, signal …

Iron-sulfur (Fe-S) clusters are ubiquitous cofactors composed of iron and inorganic sulfur.
They are required for the function of proteins involved in a wide range of activities, including …

Iron–sulfur (Fe–S) clusters (ISCs) are versatile, ancient co-factors of proteins that are
involved in electron transport, enzyme catalysis and regulation of gene expression. The …