Multiple-breath washout hyperpolarized 3He MRI was used to calculate regional parametric
images of fractional ventilation (r) as the ratio of fresh gas entering a volume unit to the total …

Quantitative measurement of regional lung ventilation is of great significance in assessment
of lung function in many obstructive and restrictive pulmonary diseases. A new technique for …

Purpose To assess the feasibility and optimize the accuracy of the multibreath wash-in
hyperpolarized helium 3 (3He) approach to ventilation measurement by using magnetic …

In this study, the effect of lung volume on quantitative measures of lung ventilation was
investigated using MRI with hyperpolarized 3He and 129Xe. Six volunteers were imaged …

Lung ventilation was mapped in seven healthy male Sprague‐Dawley rats (433±24 g) using
hyperpolarized 129Xe magnetic resonance imaging (MRI) at 3.0 T, and validated with …

RATIONALE AND OBJECTIVES: The aim of this study was to establish a standardized
procedure for the measurement of regional fractional ventilation in a healthy rat model as a …

Purpose To image respiratory dynamics and three‐dimensional (3D) ventilation during
inhalation, breath‐hold, and exhalation for evaluation of obstructive lung disease using a …

The purpose of this work was to assess the reproducibility of percentage of ventilated lung
volume (PV) measured from hyperpolarized (HP) 3He and 1H anatomical images acquired …

A novel imaging method is presented, Flip Angle Variation for Offset of RF and Relaxation
(FAVOR), for rapid and efficient measurement of rat lung ventilation using hyperpolarized …

A non‐invasive and free‐breathing hyperpolarized (HP) 3He imaging protocol for small
animals was implemented and validated on rats for lung function imaging. Animals were …