[HTML][HTML] Natural killer cell‑based immunotherapy for lung cancer: Challenges and perspectives

Y Zeng, X Lv, J Du - Oncology Reports, 2021 - spandidos-publications.com
Despite the marked success of molecular targeted therapy in lung cancer in this era of
personalized medicine, its efficacy has been limited by the presence of resistance …

Harnessing natural killer cells for lung cancer therapy

S Ma, MA Caligiuri, J Yu - Cancer Research, 2023 - AACR
Lung cancer is the leading cause of cancer-related death worldwide. Although natural killer
(NK) cells are garnering interest as a potential anticancer therapy because they selectively …

Role of natural killer cells in lung cancer

ON Aktaş, AB Öztürk, B Erman, S Erus, S Tanju… - Journal of cancer …, 2018 - Springer
Purpose One of the key immune cells involved in the pathogenesis of lung cancer is natural
killer (NK) cells and these cells are novel targets for therapeutic applications in lung cancer …

[HTML][HTML] Natural killers are made not born: how to exploit NK cells in lung malignancies

P Carrega, G Ferlazzo - Frontiers in Immunology, 2017 - frontiersin.org
In recent years, progress has been made in the characterization of natural killer (NK) cells in
lung malignancies, and we have now gained a better understanding of the frequency …

Preparation of highly activated natural killer cells for advanced lung cancer therapy

S Xie, Z Wu, L Niu, J Chen, Y Ma… - OncoTargets and …, 2019 - Taylor & Francis
Background Natural killer (NK) cells can be used as an adoptive immunotherapy to treat
cancer patients. Purpose In this study, we evaluated the efficacy of highly activated NK …

[HTML][HTML] Harnessing natural killer cells in non-small cell lung cancer

É Russell, MJ Conroy, MP Barr - Cells, 2022 - mdpi.com
Lung cancer is the leading cause of cancer-related deaths worldwide. There are two main
subtypes: small cell lung cancer (SCLC), and non-small cell lung cancer (NSCLC). NSCLC …

NK cell-based therapeutics for lung cancer

AG Pockley, P Vaupel, G Multhoff - Expert opinion on biological …, 2020 - Taylor & Francis
Introduction: Lung cancer is a devastating disease with poor overall survival. Despite
significant advances in the treatment of lung cancers using radiochemotherapy, targeted …

[HTML][HTML] Natural killer cells in the lungs

J Cong, H Wei - Frontiers in immunology, 2019 - frontiersin.org
The lungs, a special site that is frequently challenged by tumors, pathogens and other
environmental insults, are populated by large numbers of innate immune cells. Among …

Natural killer cells as a double-edged sword in cancer immunotherapy: A comprehensive review from cytokine therapy to adoptive cell immunotherapy

Y Wu, J Li, PJ Kaboli, J Shen, X Wu, Y Zhao, H Ji… - Pharmacological …, 2020 - Elsevier
Natural killer (NK) cells are immune cells which are able to kill tumor and virus-infected cells
and play an important role in both innate immunity and acquired immunity. Tumor …

Natural killer cell‐based immunotherapy in cancer: current insights and future prospects

T Sutlu, E Alici - Journal of internal medicine, 2009 - Wiley Online Library
As our understanding of the molecular mechanisms governing natural killer (NK) cell activity
increases, their potential in cancer immunotherapy is growing increasingly prominent. This …