Importance Sleep disturbance is common among patients with neurodegenerative diseases.
Examining the subcortical neuronal correlates of sleep disturbances is important to …

Introduction Sleep-wake disturbances are a common and early feature in Alzheimer's
disease (AD). The impact of early tau pathology in wake-promoting neurons (WPNs) …

Sleep/wake disturbance is a feature of almost all common age-related neurodegenerative
diseases. Although the reason for this is unknown, it is likely that this inability to maintain …

Objective To test the hypothesis that reduced slow-wave sleep, or N3 sleep, which is thought
to underlie the restorative functions of sleep, is associated with MRI markers of brain aging …

Importance Increasing evidence suggests that sleep-disordered breathing (SDB) increases
the risk of developing Alzheimer clinical syndrome. However, the brain mechanisms …

Objective: Recent research suggests that sleep disorders or changes in sleep stages or EEG
waveform precede over time the onset of the clinical signs of pathological cognitive …

Importance Disrupted sleep is common in aging and is associated with cognition. Age-
related changes to sleep are associated with multiple causes, including early Alzheimer …

Sleep disturbances and cognitive impairment are common non-motor manifestations of
Parkinson's disease (PD). Recent studies suggest that sleep spindles and slow waves play …

Objective: Sleep disturbance is common in dementia, although it is unclear whether
differences in sleep architecture precede dementia onset. We examined the associations …

Simple Summary Protein misfolding and aggregation in the brain are associated with
various neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's …