Abstract Background The Wnt/β‐catenin pathway plays a central role in the pathogenesis of
most hepatoblastomas (HBs), that is, up to 60–80% carry activating CTNNB1 mutations. HBs …

Hepatoblastoma (HB) is an embryonic neoplasm representing the most frequent malignant
liver tumour in childhood. Its tumourigenesis at the molecular level is still poorly understood …

Hepatoblastoma (HB) is the most common malignant hepatic tumor during early childhood.
Its molecular pathogenesis is still poorly understood. Mutations of adenomatous polyposis …

Hepatoblastoma is a rare malignant tumor of the liver that occurs in children at an average
age of 2 to 3 years. Epidemiologic studies have shown an increased frequency of this tumor …

Hepatoblastoma, a rare embryonic tumor that may arise sporadically or in the context of
hereditary syndromes (familial adenomatous polyposis and Beckwith–Wiedemann's) is the …

Hepatoblastomas (HBs) are embryonal tumors affecting young children and representing
the most frequent malignant liver tumors in childhood. The molecular pathogenesis of HB is …

Hepatoblastoma (HB) is the most common primary liver tumor in children. Mutations in the β‐
catenin gene that lead to constitutive activation of the Wnt pathway have been detected in a …

Hepatoblastoma (HBL) is the most common malignant liver tumor in young children. Recent
reports have shown that the β-catenin gene was frequently mutated or deleted in HBLs. To …

Germline APC pathogenic variants (PVs) are found in around 5%–10% of patients with
hepatoblastoma. 1 Previous studies have shown conflicting opinion about the necessity of …

Hepatoblastoma (HB) is a common pediatric liver cancer that could originate from
embryonal and fetal liver cells. 1 The etiology of HB is mostly unclear; however, it is well …