Single‐cell transcriptomic analysis reveals circadian rhythm disruption associated with poor prognosis and drug‐resistance in lung adenocarcinoma
L He, Y Fan, Y Zhang, T Tu, Q Zhang… - Journal of Pineal …, 2022 - Wiley Online Library
Circadian rhythm disruption (CRD) represents a major contributor to tumor proliferation.
Nonetheless, the role of CRD in the clinical prediction of cancer outcomes has not been well …
Nonetheless, the role of CRD in the clinical prediction of cancer outcomes has not been well …
[HTML][HTML] Circadian rhythm-associated clinical relevance and Tumor Microenvironment of Non-small Cell Lung Cancer
M Li, Z Chen, T Jiang, X Yang, Y Du, J Liang… - Journal of …, 2021 - ncbi.nlm.nih.gov
Objective: We aimed to explore the prognostic implication for non-small cell lung cancer
(NSCLC) based on the expression profiles of circadian clock-related genes (CCRGs), and …
(NSCLC) based on the expression profiles of circadian clock-related genes (CCRGs), and …
[HTML][HTML] Circadian clock associates with tumor microenvironment in thoracic cancers
Y Yang, G Yuan, H Xie, T Wei, D Zhu, J Cui… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
The application of cancer chronotherapy is to treat cancers based on at specific times during
circadian rhythms. Previous studies have characterized the impact of circadian clock on …
circadian rhythms. Previous studies have characterized the impact of circadian clock on …
Integrated multi-omics analysis reveals the molecular interplay between circadian clocks and cancer pathogenesis
A Pérez-Villa, G Echeverría-Garcés… - Scientific Reports, 2023 - nature.com
Circadian rhythms (CRs) are fundamental biological processes that significantly impact
human well-being. Disruption of these rhythms can trigger insufficient neurocognitive …
human well-being. Disruption of these rhythms can trigger insufficient neurocognitive …
Timing gone awry: distinct tumour suppressive and oncogenic roles of the circadian clock and crosstalk with hypoxia signalling in diverse malignancies
WH Chang, AG Lai - Journal of translational medicine, 2019 - Springer
Background The circadian clock governs a large variety of fundamentally important
physiological processes in all three domains of life. Consequently, asynchrony in …
physiological processes in all three domains of life. Consequently, asynchrony in …
Identification of TIMELESS and RORA as key clock molecules of non-small cell lung cancer and the comprehensive analysis
H Xian, Y Li, B Zou, Y Chen, H Yin, X Li, Y Pan - BMC cancer, 2022 - Springer
Background The incidence rate of non-small cell lung cancer (NSCLC) has been increasing
worldwide, and the correlation of circadian rhythm disruption with a raised risk of cancer and …
worldwide, and the correlation of circadian rhythm disruption with a raised risk of cancer and …
Circadian and immunity cycle talk in cancer destination: from biological aspects to in silico analysis
Simple Summary The circadian cycle is a natural cycle of the body repeated every 24 h,
based on a day and night rhythm, and it affects many body processes. The present article …
based on a day and night rhythm, and it affects many body processes. The present article …
CRS: a circadian rhythm score model for predicting prognosis and treatment response in cancer patients
Y Liu, S Guo, Y Sun, C Zhang, J Gan, S Ning… - Journal of Translational …, 2023 - Springer
Background Circadian rhythm regulates complex physiological activities in organisms. A
strong link between circadian dysfunction and cancer has been identified. However, the …
strong link between circadian dysfunction and cancer has been identified. However, the …
Dysregulation, functional implications, and prognostic ability of the circadian clock across cancers
It has been proposed that the circadian rhythm generally plays important roles in tumor
suppression, but there is also evidence that disruption of the canonical circadian pathway …
suppression, but there is also evidence that disruption of the canonical circadian pathway …
[HTML][HTML] A circadian rhythm-related gene signature associated with tumor immunity, cisplatin efficacy, and prognosis in bladder cancer
R Zhou, X Chen, J Liang, Q Chen, H Tian… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Circadian dysregulation involves malignant tumor initiation and progression, but the
understanding of circadian rhythm's roles in bladder cancer (BCa) remains insufficient. The …
understanding of circadian rhythm's roles in bladder cancer (BCa) remains insufficient. The …
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