Mitochondrial dynamics and mitophagy in lung disorders
Mitochondria are biosynthetic, bioenergetic, and signaling organelles which are critical for
physiological adaptations and cellular stress responses to the environment. Various …
physiological adaptations and cellular stress responses to the environment. Various …
Mitochondrial dysfunction in chronic respiratory diseases: implications for the pathogenesis and potential therapeutics
W Zhou, J Qu, S Xie, Y Sun… - Oxidative Medicine and …, 2021 - Wiley Online Library
Mitochondria are indispensable for energy metabolism and cell signaling. Mitochondrial
homeostasis is sustained with stabilization of mitochondrial membrane potential, balance of …
homeostasis is sustained with stabilization of mitochondrial membrane potential, balance of …
Targeting the mitochondria in chronic respiratory diseases
DK Chellappan, KR Paudel, NW Tan, KS Cheong… - Mitochondrion, 2022 - Elsevier
Mitochondria are one of the basic essential components for eukaryotic life survival. It is also
the source of respiratory ATP. Recently published studies have demonstrated that …
the source of respiratory ATP. Recently published studies have demonstrated that …
Mitochondrial dysfunction in lung pathogenesis
CA Piantadosi, HB Suliman - Annual review of physiology, 2017 - annualreviews.org
Remarkable new roles for mitochondria in calcium handling, apoptosis, heme turnover,
inflammation, and oxygen and nutrient sensing have been discovered for organelles that …
inflammation, and oxygen and nutrient sensing have been discovered for organelles that …
Mitochondrial redox system, dynamics, and dysfunction in lung inflammaging and COPD
Myriad forms of endogenous and environmental stress disrupt mitochondrial function by
impacting critical processes in mitochondrial homeostasis, such as mitochondrial redox …
impacting critical processes in mitochondrial homeostasis, such as mitochondrial redox …
[HTML][HTML] Targeting mitochondrial dysfunction in lung diseases: emphasis on mitophagy
A Sureshbabu, V Bhandari - Frontiers in physiology, 2013 - frontiersin.org
During mild stressful conditions, cells activate a multitude of mechanisms in an attempt to
repair or re-establish homeostasis. One such mechanism is autophagic degradation of …
repair or re-establish homeostasis. One such mechanism is autophagic degradation of …
Mitochondria in chronic obstructive pulmonary disease and lung cancer: where are we now?
HS Nam, E Izumchenko, S Dasgupta… - Biomarkers in …, 2017 - Taylor & Francis
Recent advances in mitochondrial biogenesis have provided the emerging recognition that
mitochondria do much more than 'simply providing energy for cellular function'. Currently, a …
mitochondria do much more than 'simply providing energy for cellular function'. Currently, a …
Mitochondrial dysfunction in airway disease
YS Prakash, CM Pabelick, GC Sieck - Chest, 2017 - Elsevier
There is increasing appreciation that mitochondria serve cellular functions beyond oxygen
sensing and energy production. Accordingly, it has become important to explore …
sensing and energy production. Accordingly, it has become important to explore …
Mitochondria: at the crossroads of regulating lung epithelial cell function in chronic obstructive pulmonary disease
M Aghapour, AHV Remels… - … of Physiology-Lung …, 2020 - journals.physiology.org
Disturbances in mitochondrial structure and function in lung epithelial cells have been
implicated in the pathogenesis of various lung diseases, including chronic obstructive …
implicated in the pathogenesis of various lung diseases, including chronic obstructive …
Mitochondrial dysfunction in inflammatory responses and cellular senescence: pathogenesis and pharmacological targets for chronic lung diseases
L Yue, H Yao - British journal of pharmacology, 2016 - Wiley Online Library
Mitochondria are dynamic organelles, which couple the various cellular processes that
regulate metabolism, cell proliferation and survival. Environmental stress can cause …
regulate metabolism, cell proliferation and survival. Environmental stress can cause …