Interference of alkaloids with neuroreceptors and ion channels

M Wink - Studies in natural products chemistry, 2000 - Elsevier
Alkaloids represent one of the largest classes of natural products produced not only by
plants but also by marine animals and amphibia, certain bacteria and fungi. Their general …

Allelochemical properties or the raison d'etre of alkaloids

M Wink - The alkaloids: chemistry and pharmacology, 1993 - Elsevier
Publisher Summary This chapter provides evidence that alkaloids are not waste products or
functionless molecules as formerly assumed, but rather defense compounds employed by …

Modes of action of allelochemical alkaloids: interaction with neuroreceptors, DNA, and other molecular targets

M Wink, T Schmeller, B Latz-Brüning - Journal of chemical Ecology, 1998 - Springer
Several alkaloids are toxic to insects and vertebrates and, in addition, can inhibit the growth
of bacteria and plant seedlings. In vitro assays were established to elucidate their modes of …

The ecological activity of alkaloids

KS Brown Jr, JR Trigo - The alkaloids: chemistry and pharmacology, 1995 - Elsevier
Publisher Summary This chapter discusses that modern work on alkaloid chemical ecology
is highly mechanized, using gas chromatography–mass spectroscopy (GC–MS) or high …

Utilization of alkaloids in modern medicine

T Schmeller, M Wink - Alkaloids: biochemistry, ecology, and medicinal …, 1998 - Springer
As outlined in Part III, alkaloids have evolved as a chemical defense against herbivores,
microorganisms, and viruses or against other plants (Chapters 11, 14, 15, and 16) …

[HTML][HTML] Biological activities of alkaloids: from toxicology to pharmacology

Z Adamski, LL Blythe, L Milella, SA Bufo - Toxins, 2020 - mdpi.com
Plants produce many secondary metabolites, which reveal biological activity. Among them,
alkaloids demonstrate a broad spectrum of activities. In nature, they not only are produced …

[图书][B] Alkaloids: biochemistry, ecology, and medicinal applications

MF Roberts - 2013 - books.google.com
Not since the late 1970s has a single work presented the biology of this heterogenous group
of secondary alkaloids in such depth. Alkaloids, a unique treatise featuring leaders in the …

[PDF][PDF] Plant alkaloids: main features, toxicity, and mechanisms of action

HN Matsuura, AG Fett-Neto - Plant toxins, 2015 - academia.edu
Alkaloids are one of the largest groups of plant secondary metabolites, being present in
several economically relevant plant families. Alkaloids encompass neuroactive molecules …

Plant-derived alkaloids: a promising window for neuroprotective drug discovery

A Dey, A Mukherjee - … and development of neuroprotective agents from …, 2018 - Elsevier
Alkaloids are amino acid–derived basic nitrogen-containing organic compounds, mainly
restricted to the plant kingdom. In plants, alkaloids are synthesized and accumulated as …

Neurophysiological effects of insecticides

T Narahashi - Hayes' Handbook of Pesticide Toxicology, 2010 - Elsevier
Publisher Summary This chapter describes several electrophysiological targets of
pesticides, including the voltage-gated sodium channel, acetylcholine receptors, and the …