[HTML][HTML] Tau protein as a differential biomarker of tauopathies

N Sergeant, A Delacourte, L Buée - … Acta (BBA)-Molecular Basis of Disease, 2005 - Elsevier
Microtubule-associated Tau proteins are the basic component of intraneuronal and glial
inclusions observed in many neurological disorders, the so-called tauopathies. Many …

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders

L Buée, T Bussière, V Buée-Scherrer… - Brain Research …, 2000 - Elsevier
Tau proteins belong to the family of microtubule-associated proteins. They are mainly
expressed in neurons where they play an important role in the assembly of tubulin …

Tau pathology: a marker of neurodegenerative disorders

A Delacourte, L Buée - Current opinion in neurology, 2000 - journals.lww.com
Tau is not only a basic component of neurofibrillary degeneration, but is also an aetiological
factor, as demonstrated by mutations on the tau gene responsible for frontotemporal …

Normal and pathological Tau proteins as factors for microtubule assembly

A Delacourte, L Buée - International review of cytology, 1997 - Elsevier
Tau proteins are microtubule-associated proteins. They regulate the dynamics of the
microtubule network, especially involved in the axonal transport and neuronal plasticity. Tau …

Tau and tauopathies

G Lee, CJ Leugers - Progress in molecular biology and translational …, 2012 - Elsevier
Tauopathies are age-related neurodegenerative diseases that are characterized by the
presence of aggregates of abnormally phosphorylated tau. As tau was originally discovered …

Tau as a biomarker of neurodegenerative diseases

S Schraen-Maschke, N Sergeant, CM Dhaenens… - 2008 - Taylor & Francis
The microtubule-associated protein Tau is mainly expressed in neurons of the CNS and is
crucial in axonal maintenance and axonal transport. The rationale for Tau as a biomarker of …

Tau and tauopathies

T Arendt, JT Stieler, M Holzer - Brain research bulletin, 2016 - Elsevier
Most neurodegenerative diseases are characterized by intracellular aggregates of insoluble
proteins. As for the majority of these disorders, aetiology and pathogenesis are only poorly …

Tau, where are we now?

GVW Johnson, CDC Bailey - Journal of Alzheimer's disease, 2002 - content.iospress.com
Tau is a multifunctional protein that was originally identified as a microtubule-associated
protein. Tau is primarily a neuronal protein, but it is becoming increasingly evident that tau is …

The role of tau proteoforms in health and disease

Z Waheed, J Choudhary, FH Jatala, Fatimah… - Molecular …, 2023 - Springer
Tau is a microtubule-associated binding protein in the nervous system that is known for its
role in stabilizing microtubules throughout the nerve cell. It accumulates as β-sheet-rich …

Tauopathies: classification and clinical update on neurodegenerative diseases associated with microtubule‐associated protein tau

DR Williams - Internal medicine journal, 2006 - Wiley Online Library
The majority of neurodegenerative diseases are characterized by the deposition of insoluble
protein in cells of the neuromuscular system. Advances in molecular neuropathology have …