Molecular testing and targeted therapy for non-small cell lung cancer: current status and perspectives

EN Imyanitov, AG Iyevleva, EV Levchenko - Critical reviews in oncology …, 2021 - Elsevier
Molecular testing has become a mandatory component of the non-small cell lung cancer
(NSCLC) management. The detection of EGFR, BRAF and MET mutations as well as the …

[HTML][HTML] Current landscape of non-small cell lung cancer: epidemiology, histological classification, targeted therapies, and immunotherapy

O Rodak, MD Peris-Díaz, M Olbromski… - Cancers, 2021 - mdpi.com
Simple Summary The abundance and the dynamic of the studies on NSCLC require
frequent summaries of the current achievements in the field. In our review, we aimed to …

[HTML][HTML] The evolution of therapies in non-small cell lung cancer

V Boolell, M Alamgeer, DN Watkins, V Ganju - Cancers, 2015 - mdpi.com
The landscape of advanced non-small lung cancer (NSCLC) therapies has rapidly been
evolving beyond chemotherapy over the last few years. The discovery of oncogenic driver …

[HTML][HTML] Current and future molecular testing in NSCLC, what can we expect from new sequencing technologies?

S Garinet, P Laurent-Puig, H Blons… - Journal of clinical …, 2018 - mdpi.com
Recent changes in lung cancer care, including new approvals in first line and the
introduction of high-throughput molecular technologies in routine testing led us to question …

[HTML][HTML] The evolving landscape of biomarker testing for non-small cell lung cancer in Europe

KM Kerr, F Bibeau, E Thunnissen, J Botling, A Ryška… - Lung Cancer, 2021 - Elsevier
The discovery of oncogenic driver mutations rendering non-small cell lung cancer (NSCLC)
targetable by small-molecule inhibitors, and the development of immunotherapies, have …

Emerging targeted therapies for the treatment of non-small cell lung cancer

PR Halliday, CM Blakely, TG Bivona - Current oncology reports, 2019 - Springer
Abstract Purpose of Review Lung cancer remains the leading cause of cancer-related
mortality worldwide. Genetic and molecular profiling of non-small cell lung cancer (NSCLC) …

[HTML][HTML] Future perspective for the application of predictive biomarker testing in advanced stage non-small cell lung cancer

VD de Jager, W Timens, A Bayle, J Botling… - The Lancet Regional …, 2024 - thelancet.com
For patients with advanced stage non-small cell lung cancer (NSCLC), treatment strategies
have changed significantly due to the introduction of targeted therapies and immunotherapy …

[HTML][HTML] The storm of NGS in NSCLC diagnostic-therapeutic pathway: How to sun the real clinical practice

G De Maglio, G Pasello, M Dono, M Fiorentino… - Critical Reviews in …, 2022 - Elsevier
The increasing number of approved drugs along with next generation sequencing (NGS)
technologies look out as potential revolution of biomolecular characterization of non-small …

Precision medicine in non-small cell lung cancer: Current applications and future directions

SR Yang, AM Schultheis, H Yu, D Mandelker… - Seminars in cancer …, 2022 - Elsevier
Advances in biomarkers, targeted therapies, and immuno-oncology have transformed the
clinical management of patients with advanced NSCLC. For oncogene-driven tumors, there …

[HTML][HTML] Advances in genomic data and biomarkers: revolutionizing NSCLC diagnosis and treatment

JC Restrepo, D Dueñas, Z Corredor, Y Liscano - Cancers, 2023 - mdpi.com
Simple Summary In the field of non-small cell lung cancer (NSCLC), there have been
significant advancements in genomic data and bioinformatics tools, which have improved …