Parkinson's disease (PD) is characterized by the progressive and asymmetrical
degeneration of the nigrostriatal dopamine neurons and the unilateral presentation of the …

In Parkinson disease (PD), the subthalamic nucleus (STN) becomes hyperactive
(disinhibited), which is reported to cause excitotoxic damage to midbrain dopaminergic …

Subthalamic nucleus (STN) is a target of choice for the neurosurgical treatment of
Parkinson's disease (PD). The therapeutic effect of STN lesion in PD is classically ascribed …

The onset of Parkinson's disease (PD) is characterized by focal motor features in one body
part, which are usually correlated with greater dopaminergic depletion in the contralateral …

Inactivation of the subthalamic nucleus (STN) by deep brain stimulation or lesioning can
ameliorate symptoms in Parkinson'disease (PD) and may alter the underlying progressive …

The subthalamic nucleus (STN) receives direct dopaminergic innervation from the
substantia nigra pars compacta, but the importance of this input in the pathophysiology of …

The motor symptoms of Parkinson's disease (PD) are linked to abnormally correlated and
coherent activity in the cortex and subthalamic nucleus (STN). However, in parkinsonian …

Parkinson's disease (PD) is an asymmetric neurodegenerative disorder, and secondary
adaptive mechanisms of the less-affected side could potentially compensate for …

Parkinson's disease (PD) is a neurological disorder characterized by the manifestation of
motor symptoms, such as akinesia, muscle rigidity and tremor at rest. These symptoms are …

Parkinson's disease (PD) is characterized by the progressive degeneration of substantia
nigra (SN) dopamine neurons, involving a multifactorial cascade of pathogenic events. Here …