Anti-fatigue effect of phlorizin on exhaustive exercise-induced oxidative injury mediated by Nrf2/ARE signaling pathway in mice

C Ma, Y Deng, R Xiao, F Xu, M Li, Q Gong… - European Journal of …, 2022 - Elsevier
Oxidative stress plays a crucial role in fatigue, thus it is of significance to develop safe and
efficient antioxidant to prevent fatigue. Phlorizin (PHZ) is a major active ingredient of …

[HTML][HTML] Trilobatin, a naturally occurring food additive, ameliorates exhaustive exercise-induced fatigue in mice: involvement of Nrf2/ARE/ferroptosis signaling pathway

R Xiao, Y Wei, Y Zhang, F Xu, C Ma, Q Gong… - Frontiers in …, 2022 - frontiersin.org
Nrf2-mediated oxidative stress is a promising target of exhaustive exercise-induced fatigue
(EEIF). Trilobatin (TLB) is a naturally occurring food additive with antioxidant effect and Nrf2 …

[HTML][HTML] Phloroglucinol Inhibits Oxidative-Stress-Induced Cytotoxicity in C2C12 Murine Myoblasts through Nrf-2-Mediated Activation of HO-1

C Park, HJ Cha, H Hwangbo, SY Ji, DH Kim… - International Journal of …, 2023 - mdpi.com
Phloroglucinol is a class of polyphenolic compounds containing aromatic phenyl rings and
is known to have various pharmacological activities. Recently, we reported that this …

Antifatigue Effect of Luteolin‐6‐C‐Neohesperidoside on Oxidative Stress Injury Induced by Forced Swimming of Rats through Modulation of Nrf2/ARE Signaling …

F Duan, Y Guo, J Li, K Yuan - Oxidative Medicine and Cellular …, 2017 - Wiley Online Library
Luteolin‐6‐C‐neohesperidoside (LN) is a flavonoid isolated from moso bamboo leaf. This
study was performed to evaluate the antifatigue effect of LN on a rat model undergoing the …

Anti-fatigue effect of anwulignan via the NRF2 and PGC-1α signaling pathway in mice

X Zhang, S Jing, H Lin, W Sun, W Jiang, C Yu, J Sun… - Food & Function, 2019 - pubs.rsc.org
Objective: To examine the anti-fatigue function of anwulignan from Schisandra and its
underlying mechanism. Methods: After an excessive fatigue mouse model was created …

[HTML][HTML] Anti-Fatigue Effects of Lycium barbarum Polysaccharide and Effervescent Tablets by Regulating Oxidative Stress and Energy Metabolism in Rats

Y Peng, L Zhao, K Hu, Y Yang, J Ma, Y Zhai… - International Journal of …, 2022 - mdpi.com
The purpose of this study was to investigate the anti-fatigue effect of natural Lycium
barbarum polysaccharide (LBP) during exercise, develop a functional anti-fatigue …

Apple phlorizin attenuates oxidative stress in Drosophila melanogaster

H Wang, Z Sun, D Liu, X Li, R Rehman… - Journal of food …, 2019 - Wiley Online Library
Apple phlorizin has a lot of applications owing to its antioxidant and hepatoprotective
properties. This study explored the antioxidant effects and life span‐prolonging activity of …

Puerarin suppresses MPP+/MPTP-induced oxidative stress through an Nrf2-dependent mechanism

X Li, J Zhang, X Zhang, M Dong - Food and Chemical Toxicology, 2020 - Elsevier
In this study, we hypothesized that anti-parkinsonian effect of puerarin is attributable to its
antioxidant properties via Nrf2-dependent glutathione (GSH) biosynthesis mechanism …

Phillyrin Mitigates Apoptosis and Oxidative Stress in Hydrogen Peroxide‐Treated RPE Cells through Activation of the Nrf2 Signaling Pathway

Y Du, L You, B Ni, N Sai, W Wang… - Oxidative medicine …, 2020 - Wiley Online Library
Oxidative stress‐induced dysfunction or apoptosis in retinal pigment epithelial (RPE) cells is
an important cause of dry age‐related macular degeneration (AMD). Although phillyrin has …

[HTML][HTML] Anti-fatigue activity of parsley (Petroselinum crispum) flavonoids via regulation of oxidative stress and gut microbiota in mice

Y Wang, Y Zhang, M Hou, W Han - Journal of Functional Foods, 2022 - Elsevier
Parsley, a common vegetable, is widely used as a condiment because its flavor. However,
its biological functionality remains largely ignored. In this study, the antioxidant activity …