Obesity and multiple myeloma: Emerging mechanisms and perspectives

A Tentolouris, I Ntanasis-Stathopoulos… - Seminars in Cancer …, 2023 - Elsevier
Obesity is a global pandemic that has been associated with the development of breast,
endometrial, large intestine, renal, esophageal, and pancreatic cancer. Obesity is also …

It is worth the weight: obesity and the transition from monoclonal gammopathy of undetermined significance to multiple myeloma

R Choa, C Panaroni, R Bhatia, N Raje - Blood Advances, 2023 - ashpublications.org
The overweight/obesity epidemic is a serious public health concern that affects> 40% of
adults globally and increases the risk of numerous chronic diseases, such as type 2 …

Overweight/obesity and monoclonal gammopathy of undetermined significance

R Georgakopoulou, A Andrikopoulou… - … Myeloma and Leukemia, 2021 - Elsevier
Background Obesity and high body mass index (BMI) are associated with increased
incidence of multiple myeloma (MM). MM usually evolves from a precursor asymptomatic …

The skinny on obesity and plasma cell myeloma: a review of the literature

KR Carson, ML Bates, MH Tomasson - Bone marrow transplantation, 2014 - nature.com
Despite tremendous advances in treatments for myeloma in the past decade, the disease
remains incurable in the majority of patients. Here, we review recent data demonstrating an …

A comprehensive review of the impact of obesity on plasma cell disorders

R Parikh, SM Tariq, CR Marinac, UA Shah - Leukemia, 2022 - nature.com
Multiple myeloma (MM) remains an incurable plasma cell malignancy. Although little is
known about the etiology of MM, several metabolic risk factors such as obesity, diabetes …

[HTML][HTML] The relation of obesity-related hormonal and cytokine levels with multiple myeloma and non-Hodgkin lymphoma

HD Hosgood, MJ Gunter, N Murphy, TE Rohan… - Frontiers in …, 2018 - frontiersin.org
This article presents the first detailed overview of the mechanisms that may underlie the
relation of obesity with B-cell non-Hodgkin lymphomas (NHLs) and multiple myeloma (MM) …

Obesity and risk of monoclonal gammopathy of undetermined significance and progression to multiple myeloma: a population-based study

M Thordardottir, EK Lindqvist, SH Lund… - Blood …, 2017 - ashpublications.org
All multiple myeloma (MM) cases are preceded by the premalignant state monoclonal
gammopathy of undetermined significance (MGUS). Results from previous studies show a …

Adipokines, adiposity, and bone marrow adipocytes: Dangerous accomplices in multiple myeloma

EV Morris, CM Edwards - Journal of Cellular Physiology, 2018 - Wiley Online Library
Obesity has become a global epidemic influencing the establishment and progression of a
wide range of diseases, such as diabetes, cardiovascular disease, and cancer. In 2016 …

Decreased body mass index is associated with poor prognosis in patients with multiple myeloma

SH Jung, DH Yang, JS Ahn, SS Lee, SY Ahn… - Annals of …, 2014 - Springer
Obesity increases morbidity in and mortality of patients with various types of cancer.
However, the proportion of obese individuals in Asia is smaller than that in Western …

Correlation Between Bariatric Surgery and the Risk of Multiple Myeloma: Results from an Evidence-Based Strategy

Q Wu, T Zhao, C Zhu, M Da - Obesity Surgery, 2024 - Springer
Objective We conducted a meta-analysis of current literature to assess whether bariatric
surgery (BS) has a positive effect on reducing the risk of multiple myeloma (MM). Methods …