[HTML][HTML] Research and development of new tuberculosis vaccines: a review
LK Schrager, RC Harris, J Vekemans - F1000Research, 2018 - ncbi.nlm.nih.gov
Tuberculosis kills more people worldwide than any other single infectious disease agent, a
threat made more dire by the spread of drug-resistant strains of Mycobacterium tuberculosis …
threat made more dire by the spread of drug-resistant strains of Mycobacterium tuberculosis …
[HTML][HTML] Status of vaccine research and development of vaccines for tuberculosis
TG Evans, L Schrager, J Thole - Vaccine, 2016 - Elsevier
TB is now the single pathogen that causes the greatest mortality in the world, at over 1.6
million deaths each year. The widely used the 90 year old BCG vaccine appears to have …
million deaths each year. The widely used the 90 year old BCG vaccine appears to have …
[HTML][HTML] Current and novel approaches to vaccine development against tuberculosis
MJ Cayabyab, L Macovei… - Frontiers in cellular and …, 2012 - frontiersin.org
Antibiotics and vaccines are the two most successful medical countermeasures that humans
have created against a number of pathogens. However a select few eg, Mycobacterium …
have created against a number of pathogens. However a select few eg, Mycobacterium …
[HTML][HTML] Tuberculosis vaccines–state of the art, and novel approaches to vaccine development
C da Costa, B Walker, A Bonavia - International Journal of Infectious …, 2015 - Elsevier
The quest for a vaccine that could have a major impact in reducing the current global burden
of TB disease in humans continues to be extremely challenging. Significant gaps in our …
of TB disease in humans continues to be extremely challenging. Significant gaps in our …
[HTML][HTML] Development of new tuberculosis vaccines: a global perspective on regulatory issues
MJ Brennan, U Fruth, J Milstien, R Tiernan… - PLoS …, 2007 - journals.plos.org
Development of New Tuberculosis Vaccines: A Global Perspective on Regulatory Issues |
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Designing tuberculosis vaccine efficacy trials–lessons from recent studies
AM Ginsberg - Expert Review of Vaccines, 2019 - Taylor & Francis
Introduction: Tuberculosis (TB) is the leading infectious killer globally and new TB vaccines
will be crucial to ending the epidemic. Since the introduction in 1921 of the only currently …
will be crucial to ending the epidemic. Since the introduction in 1921 of the only currently …
[HTML][HTML] Tuberculosis vaccine development: from classic to clinical candidates
J Li, A Zhao, J Tang, G Wang, Y Shi, L Zhan… - European Journal of …, 2020 - Springer
Abstract Bacillus Calmette-Guérin (BCG) has been in use for nearly 100 years and is the
only licensed TB vaccine. While BCG provides protection against disseminated TB in infants …
only licensed TB vaccine. While BCG provides protection against disseminated TB in infants …
Successes and failures in human tuberculosis vaccine development
R Zenteno-Cuevas - Expert opinion on biological therapy, 2017 - Taylor & Francis
Introduction: Tuberculosis (TB) is an infectious disease caused mainly by Mycobacterium
tuberculosis. In 2016, the WHO estimated 10.5 million new cases and 1.8 million deaths …
tuberculosis. In 2016, the WHO estimated 10.5 million new cases and 1.8 million deaths …
[HTML][HTML] Vaccines against tuberculosis: where are we and where do we need to go?
THM Ottenhoff, SHE Kaufmann - PLoS pathogens, 2012 - journals.plos.org
In this review we discuss recent progress in the development, testing, and clinical evaluation
of new vaccines against tuberculosis (TB). Over the last 20 years, tremendous progress has …
of new vaccines against tuberculosis (TB). Over the last 20 years, tremendous progress has …
The current state of tuberculosis vaccines
DA Hokey, A Ginsberg - Human vaccines & immunotherapeutics, 2013 - Taylor & Francis
Tuberculosis continues to persist despite widespread use of BCG, the only licensed vaccine
to prevent TB. BCG's limited efficacy coupled with the emergence of drug-resistant strains of …
to prevent TB. BCG's limited efficacy coupled with the emergence of drug-resistant strains of …