The concept of cell fate relates to the future identity of a cell, and its daughters, which is
obtained via cell differentiation and division. Understanding, predicting, and manipulating …

Cellular differentiation is a common underlying feature of all multicellular organisms through
which naïve cells progressively become fate restricted and develop into mature cells with …

Fueled by recent advances in single cell biology, we are moving away from qualitative and
undersampled assessments of cell identity, toward building quantitative, high-resolution cell …

Correct and timely lineage decisions are critical for normal embryonic development and
homeostasis of adult tissues. Therefore, the search for fundamental principles that underlie …

Mapping the paths that stem and progenitor cells take en route to differentiate and
elucidating the underlying molecular controls are key goals in developmental and stem cell …

Understanding the molecular control of cell fates is central to stem cell research. Such
insight requires quantification of molecular and cellular behavior at the single-cell level …

The stem/progenitor cell has long been regarded as a central cell type in development,
homeostasis, and regeneration, largely owing to its robust self-renewal and multilineage …

INTRODUCTION Understanding the differentiation of stem cells into the vast amount of cell
types that form the human body is a central problem of basic and medical science. The …

High‐throughput‐omics techniques have revolutionised biology, allowing for thorough and
unbiased characterisation of the molecular states of biological systems. However, cellular …

Cell fate decisions play a pivotal role in development, but technologies for dissecting them
are limited. We developed a multifunction new method, Topographer, to construct a …