[HTML][HTML] UPLC-Q/TOF-MS-Based Serum Metabolomics Reveals Hypoglycemic Effects of Rehmannia glutinosa, Coptis chinensis and Their Combination on High-Fat …

Z Qin, W Wang, D Liao, X Wu, X Li - International journal of molecular …, 2018 - mdpi.com
Diabetes is a worldwide severe health issue which causes various complications. This study
aimed to evaluate the hypoglycemic effects of Rehmannia glutinosa (RG), Coptis chinensis …

[HTML][HTML] Revealing hypoglycemic and hypolipidemic mechanism of Xiaokeyinshui extract combination on streptozotocin-induced diabetic mice in high sucrose/high fat …

Z Xiang, H Xie, Q Tong, J Pan, L Wan, J Fang… - Biomedicine & …, 2021 - Elsevier
Type 2 diabetic mellitus (T2DM), often accompanied by disorders of glucose and lipid
metabolism, has troubled hundreds of millions of people. Xiaokeyinshui extract combination …

[HTML][HTML] Untargeted metabolomics analysis of the anti-diabetic effect of Red ginseng extract in Type 2 diabetes Mellitus rats based on UHPLC-MS/MS

Z Yang, D Wang, Y Li, X Zhou, T Liu, C Shi, R Li… - Biomedicine & …, 2022 - Elsevier
Red ginseng is a traditional Chinese herbal medicine that has long been used to treat
diabetes, and its blood sugar-lowering activity has been confirmed. However, the …

Serum metabolomic analysis of the anti-diabetic effect of Ginseng berry in type II diabetic rats based on ultra high-performance liquid chromatography-high resolution …

H Wang, R Huang, H Li, L Jiao, S Liu, W Wu - Journal of Pharmaceutical …, 2021 - Elsevier
Serum metabolomic method was used to investigated the anti-diabetic effects and
mechanism of Ginseng berry (GB) on high-fat diet combined streptozotocin induced type II …

[HTML][HTML] UHPLC-MS-Based serum and urine metabolomics reveals the anti-diabetic mechanism of ginsenoside Re in type 2 diabetic rats

H Wang, Y Teng, S Li, Y Li, H Li, L Jiao, W Wu - Molecules, 2021 - mdpi.com
Panax ginseng was employed in the treatment of “Xiao-Ke” symptom, which nowadays
known as diabetes mellitus, in traditional Chinese medicine for more than a thousand years …

Metabolomics-based evidence of the hypoglycemic effect of Ge-Gen-Jiao-Tai-Wan in type 2 diabetic rats via UHPLC-QTOF/MS analysis

W Wang, L Zhao, Z He, N Wu, Q Li, X Qiu… - Journal of …, 2018 - Elsevier
Abstract Ethnopharmacological relevance Ge-Gen-Jiao-Tai-Wan (GGJTW) formula, derived
from traditional Chinese herbal medicine, is composed of Pueraria montana var. lobata …

[HTML][HTML] Revealing the hypoglycemic effects and mechanism of GABA-rich germinated Adzuki beans on T2DM mice by untargeted serum metabolomics

X Jiang, Q Xu, A Zhang, Y Liu, Z Li, H Tang… - Frontiers in …, 2021 - frontiersin.org
Type 2 diabetes mellitus (T2DM) is one of the most common metabolic diseases, and
exploring strategies to prevent and treat diabetes has become extremely important. In recent …

[HTML][HTML] A metabolomics approach to investigate kukoamine B—A potent natural product with anti-diabetic properties

YY Li, DA Stewart, XM Ye, LH Yin… - Frontiers in …, 2019 - frontiersin.org
Due to the surge in type 2 diabetes mellitus (T2DM), treatments for chronic metabolic
dysregulations with fewer side-effects are sought. Lycii Cortex (LyC), a traditional Chinese …

Effect of Ipomoea aquatica ethanolic extract in streptozotocin (STZ) induced diabetic rats via 1H NMR-based metabolomics approach

AAB Sajak, A Mediani, NSM Dom, C Machap, M Hamid… - Phytomedicine, 2017 - Elsevier
Background Ipomoea aquatica (locally known as “kangkung”) has previously been reported
to have hypoglycemic activities on glucose level in diabetes patients. However, the effect of …

Explore of the beneficial effects of Huang-Lian-Jie-Du Decoction on diabetic encephalopathy in db/db mice by UPLC-Q-Orbitrap HRMS/MS based untargeted …

WJ He, DM Cao, YB Chen, JJ Shi, T Hu… - … of Pharmaceutical and …, 2021 - Elsevier
Diabetic encephalopathy (DE) is a severe diabetic complication with cognitive dysfunction.
Huang-Lian-Jie-Du Decoction (HLJDD), a famous traditional Chinese formula, is effective for …