Background Our aim was to determine whether the change in left ventricular (LV) mass in
response to antihypertensive treatment could be predicted by multivariate analysis of single …

Background: The renin-angiotensin-aldosterone system (RAAS) is important for the
development of hypertension, and several antihypertensive drugs target this system. Our …

Background Our aim was to determine if gene polymorphisms in the renin–angiotensin–
aldosterone system (RAAS) were related to the degree of change in left ventricular …

Background Dyslipidemia has been associated with hypertension. The present study
explored if polymorphisms in genes encoding proteins in lipid metabolism could be used as …

Left ventricular hypertrophy (LVH), a common consequence of systemic hypertension
associated with poor clinical outcome, is also a potentially reversible condition. Here, we …

Left ventricular hypertrophy (LVH) is an important predictor of cardiovascular morbidity and
mortality in hypertensives. Consequently, a better understanding of the underlying causal …

Stimulation of insulin-like growth factor (IGF)-1 receptor by IGF-1 and insulin strongly
induces cardiomyocyte hypertrophy. In this study, we assessed the hypothesis that genetic …

Three subtypes of β-adrenoceptor, β 1, β 2 and β 3, are involved in the sympathetic nervous
system, which plays an important role in the development of hypertension and hypertensive …

Objectives Although blood pressure is considered the major determinant of left ventricular
hypertrophy in hypertension, genetic variability is increasingly being considered among the …

Background: Angiotensin II, via the angiotensin II type 1 (AT1) receptor, may mediate
myocardial fibrosis and myocyte hypertrophy seen in hypertensive left ventricular (LV) …