Next-generation multitarget stool DNA test for colorectal cancer screening

TF Imperiale, K Porter, J Zella, ZD Gagrat… - … England Journal of …, 2024 - Mass Medical Soc
Background A next-generation multitarget stool DNA test, including assessments of DNA
molecular markers and hemoglobin level, was developed to improve the performance of …

[HTML][HTML] Multitarget stool DNA testing for colorectal-cancer screening

TF Imperiale, DF Ransohoff, SH Itzkowitz… - … England Journal of …, 2014 - Mass Medical Soc
Background An accurate, noninvasive test could improve the effectiveness of colorectal-
cancer screening. Methods We compared a noninvasive, multitarget stool DNA test with a …

Stool screening for colorectal cancer: evolution from occult blood to molecular markers

DA Ahlquist, AP Shuber - Clinica Chimica Acta, 2002 - Elsevier
Background: Colorectal cancer is the second leading cause of malignant death, and better
preventive strategies are needed. Participation rates for colorectal cancer screening remain …

Fecal DNA testing for colorectal cancer screening

JM Carethers - Annual Review of Medicine, 2020 - annualreviews.org
Fecal (or stool) DNA examination is a noninvasive strategy recommended by several
medical professional societies for colorectal cancer (CRC) screening in average-risk …

[HTML][HTML] Stool DNA testing for screening detection of colorectal neoplasia in Alaska native people

DG Redwood, ED Asay, ID Blake, PE Sacco… - Mayo Clinic …, 2016 - Elsevier
Objective To assess the accuracy of a multitarget stool DNA test (MT-sDNA) compared with
fecal immunochemical testing for hemoglobin (FIT) for detection of screening-relevant …

[HTML][HTML] Multitarget stool DNA test performance in an average-risk colorectal cancer screening population

LJW Bosch, V Melotte, S Mongera… - Official journal of the …, 2019 - journals.lww.com
METHODS: Whole stool samples (n= 1,047) were prospectively collected and subjected to
an MT-sDNA test, which tests for KRAS mutations, NDRG4 and BMP3 promoter methylation …

Multi-target stool DNA test: a new high bar for noninvasive screening

DA Ahlquist - Digestive diseases and sciences, 2015 - Springer
Stool DNA testing has evolved into what is now a highly accurate and well-validated test for
the screen detection of colorectal neoplasia. An optimized and automated multi-target stool …

Stool DNA and occult blood testing for screen detection of colorectal neoplasia

DA Ahlquist, DJ Sargent, CL Loprinzi… - Annals of internal …, 2008 - acpjournals.org
Background: Stool DNA testing is a new approach to colorectal cancer detection. Few data
are available from the screening setting. Objective: To compare stool DNA and fecal blood …

Sensitivity and specificity of a stool DNA multitarget assay panel for the detection of advanced colorectal neoplasia

KS Tagore, MJ Lawson, JA Yucaitis, R Gage… - Clinical colorectal …, 2003 - Elsevier
Colorectal cancer is the second-leading cause of cancer death. New noninvasive options for
screening capable of diagnosing cancer at an early stage are needed to improve …

Clinical performance of an automated stool DNA assay for detection of colorectal neoplasia

GP Lidgard, MJ Domanico, JJ Bruinsma, J Light… - Clinical …, 2013 - Elsevier
Background & Aims Colorectal cancer (CRC) and advanced precancers can be detected
noninvasively by analyses of exfoliated DNA markers and hemoglobin in stool. Practical and …