Coronaviruses (CoVs) assemble by budding into the lumen of the intermediate compartment
(IC) at the endoplasmic reticulum (ER)-Golgi interface. However, why CoVs have chosen the …

Coronaviruses (CoV) are enveloped positive‐strand RNA viruses that induce different
membrane rearrangements in infected cells in order to efficiently replicate and assemble …

The envelopes of coronaviruses (CoVs) contain primarily three proteins; the two major
glycoproteins spike (S) and membrane (M), and envelope (E), a non-glycosylated protein …

Coronavirus spike protein genes were expressed in vitro by using the recombinant vaccinia
virus expression system. Recombinant spike proteins were expressed at the cell surface and …

Enveloped viruses need to fuse with a host cell membrane in order to deliver their genome
into the host cell. While some viruses fuse with the plasma membrane, many viruses are …

Coronaviruses are assembled by budding into a pre-Golgi compartment from which they are
transported along the secretory pathway to leave the cell. In cultured epithelial cells, they are …

Coronaviruses (CoVs) assemble by budding into the lumen of the early Golgi complex prior
to exocytosis. The small CoV envelope (E) protein plays roles in assembly, virion release …

Coronavirus budding at the endoplasmic reticulum-Golgi intermediate compartment
(ERGIC) requires accumulation of the viral envelope proteins at this point in the secretory …

Publisher Summary This chapter describes the interactions between the different structural
components of the viruses and discusses their relevance for the process of virion formation …

One missing link in the coronavirus assembly is the physical interaction between two crucial
structural proteins, the membrane (M) and envelope (E) proteins. In this study, we …