The Immune Interplay between the Host and the Pathogen in Aspergillus fumigatus Lung Infection

H Sales-Campos, L Tonani… - BioMed research …, 2013 - Wiley Online Library
The interplay between Aspergillus fumigatus and the host immune response in lung
infection has been subject of studies over the last years due to its importance in …

[HTML][HTML] The innate immune response to Aspergillus fumigatus

V Balloy, M Chignard - Microbes and infection, 2009 - Elsevier
Despite the development of new treatments, the mortality due to invasive pulmonary
aspergillosis remains above 50%, reaching 95% in certain situations. The battle against …

[HTML][HTML] Bronchial epithelial cells on the front line to fight lung infection-causing Aspergillus fumigatus

J Bigot, L Guillot, J Guitard, M Ruffin, H Corvol… - Frontiers in …, 2020 - frontiersin.org
Aspergillus fumigatus is an environmental filamentous fungus that can be pathogenic for
humans, wherein it is responsible for a large variety of clinical forms ranging from allergic …

Innate lung defense during invasive aspergillosis: new mechanisms

JM Garth, C Steele - Journal of innate immunity, 2017 - karger.com
Invasive aspergillosis (IA) is one of the most difficult to treat and, consequently, one of the
most lethal fungal infections known to man. Continued use of immunosuppressive agents …

Pathogenicity and virulence of Aspergillus fumigatus

K Earle, C Valero, DP Conn, G Vere, PC Cook… - Virulence, 2023 - Taylor & Francis
Pulmonary infections caused by the mould pathogen Aspergillus fumigatus are a major
cause of morbidity and mortality globally. Compromised lung defences arising from …

The pathobiology of Aspergillus fumigatus

JP Latgé - Trends in microbiology, 2001 - cell.com
Aspergillus fumigatus is the most prevalent airborne fungal pathogen in developed
countries, and in immunocompromised patients causes a usually fatal invasive aspergillosis …

New insights into invasive aspergillosis-from the pathogen to the disease

U Binder, C Lass-Florl - Current pharmaceutical design, 2013 - ingentaconnect.com
Disease manifestations with Aspergillus spp. are very diverse and dependent on interaction
between the fungus and the host. Invasive aspergillosis (IA) is the most severe form of …

Aspergillus fumigatus and Aspergillosis in 2019

JP Latgé, G Chamilos - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

[HTML][HTML] Humoral Immunity Against Aspergillus fumigatus

S Dellière, V Aimanianda - Mycopathologia, 2023 - Springer
Aspergillus fumigatus is one the most ubiquitous airborne opportunistic human fungal
pathogens. Understanding its interaction with host immune system, composed of cellular …

The innate immune response to Aspergillus fumigatus at the alveolar surface

A Margalit, K Kavanagh - FEMS microbiology reviews, 2015 - academic.oup.com
Aspergillus fumigatus is an ubiquitous, saprophytic mould that forms and releases airborne
conidia which are inhaled by humans on a daily basis. When the immune system is …