[HTML][HTML] Bleeding with intensive versus guideline antiplatelet therapy in acute cerebral ischaemia

LJ Woodhouse, JP Appleton, H Christensen… - Scientific Reports, 2023 - nature.com
Intensive antiplatelet therapy did not reduce recurrent stroke/transient ischaemic attack (TIA)
events as compared with guideline treatment in the Triple Antiplatelets for Reducing …

[HTML][HTML] Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia …

PM Bath, LJ Woodhouse, JP Appleton, M Beridze… - The Lancet, 2018 - thelancet.com
Background Intensive antiplatelet therapy with three agents might be more effective than
guideline treatment for preventing recurrent events in patients with acute cerebral …

Statistical analysis plan for the 'Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke'(TARDIS) trial

PMW Bath, K Robson, LJ Woodhouse… - … journal of stroke, 2015 - journals.sagepub.com
Rationale Antiplatelet agents such as aspirin, clopidogrel and dipyridamole are effective in
reducing the risk of recurrence after a stroke. Importantly, the risk of recurrence is highest …

Safety and efficacy of intensive vs. guideline antiplatelet therapy in high-risk patients with recent ischemic stroke or transient ischemic attack: rationale and design of …

TARDIS Trial Investigators - International Journal of Stroke, 2015 - journals.sagepub.com
Rationale The risk of recurrence following a stroke or transient ischemic attack is high,
especially immediately after the event. Hypothesis Because two antiplatelet agents are …

Early time course of major bleeding on antiplatelet therapy after TIA or ischemic stroke

NA Hilkens, A Algra, LJ Kappelle, PM Bath, L Csiba… - Neurology, 2018 - AAN Enterprises
Objective To study the early time course of major bleeding and its subtypes in patients with
cerebral ischemia on dual and single antiplatelet therapy. Methods We performed a post hoc …

Clinical effects of dual antiplatelet therapy or aspirin monotherapy after acute minor ischemic stroke or transient ischemic attack, a meta-analysis

F Condello, G Liccardo… - Current Pharmaceutical …, 2021 - ingentaconnect.com
Background: Evidence about the use of dual antiplatelet therapy (DAPT) with aspirin and
P2Y12 inhibitors in patients with acute minor ischemic stroke or transient ischemic attack …

Baseline characteristics of the 3096 patients recruited into the 'Triple Antiplatelets for Reducing Dependency after Ischemic Stroke'trial

PMW Bath, JP Appleton, M Beridze… - … Journal of Stroke, 2017 - journals.sagepub.com
Background The risk of recurrence following ischemic stroke or transient ischemic attack is
highest immediately after the event. Antiplatelet agents are effective in reducing the risk of …

In the THALES trial, past, present, and future meet

ZX Li, XW Xie, Y Xian - Neuroscience Bulletin, 2021 - Springer
Patients with minor ischemic stroke or a high-risk transient ischemic attack (TIA) face a high
risk of recurrent stroke or other vascular events. The risk is particularly high in the first few …

[HTML][HTML] Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial

RAS Salman, MS Dennis, PAG Sandercock… - The Lancet, 2019 - thelancet.com
Background Antiplatelet therapy reduces the risk of major vascular events for people with
occlusive vascular disease, although it might increase the risk of intracranial haemorrhage …

Critique on the use of early short-term dual antiplatelet therapy following minor acute cerebral ischemic events

M Moussouttas, NIH Papamitsakis - Cerebrovascular Diseases, 2020 - karger.com
Background: Two recent cerebrovascular studies, Clopidogrel (Clo) in High-risk patients
with Acute Nondisabling Cerebrovascular Events (CHANCE) and Platelet-Oriented …