Pharmacogenomics is the study of genetic variants that impact drug effects through changes
in a drug's pharmacokinetics and pharmacodynamics. Pharmacogenomics is being …

Pain is a common symptom that can be complex to treat. Analgesic medications are the
mainstay treatment, but there is wide interindividual variability in analgesic response and …

Chronic pain affects approximately one in five adults, resulting in a greatly reduced quality of
life and a higher risk of developing co-morbidities such as depression. Available treatments …

The experience of chronic pain is one of the commonest reasons for seeking medical
attention, being a major issue in clinical practice. While pain is a universal experience, only …

Objective: To provide an overview of clinical recommendations regarding genomic medicine
relating to pain management and opioid use disorder. Data Sources: A literature review was …

Medicine has been continuously challenged, as well as stimulated, by the extraordinary
variability in patient response to pharmacotherapy. The new age of identification of risk …

Pharmacological, surgical, psychological, and alternative medicine approaches for the
treatment of chronic pain, including neuropathic pain, provide only partial relief for most …

Successful pain management requires the delivery of analgesia with minimal risk of adverse
drug reactions. Nonsteroidal anti-inflammatory drugs and opioids remain the mainstay of …

Introduction: Opioid analgesics are widely used as effective analgesics for the treatment of
moderate-to-severe pain. However, the analgesic efficacy of opioids is well known to vary …

Objective The experience of chronic pain is one of the commonest reasons individuals seek
medical attention, making the management of chronic pain a major issue in clinical practice …