Transplant suitability of rejected human donor lungs with prolonged cold ischemia time in low-flow acellular and high-flow cellular ex vivo lung perfusion systems

T Okamoto, D Wheeler, CF Farver, KR McCurry - Transplantation, 2019 - journals.lww.com
Background. Ex vivo lung perfusion (EVLP) has the potential to increase the number of
donor lungs available for lung transplantation (LTx). While the current maximum cold …

[HTML][HTML] Ex vivo lung perfusion with perfusate purification for human donor lungs following prolonged cold storage

D Wei, F Gao, Z Yang, W Wang, Y Chen… - Annals of …, 2020 - ncbi.nlm.nih.gov
Background Ex vivo lung perfusion (EVLP) has developed as the most effective technique
for estimating marginal donor lungs. This study attempted to extend the EVLP running time …

Standard donor lung procurement with normothermic ex vivo lung perfusion: a prospective randomized clinical trial

A Slama, L Schillab, M Barta, A Benedek… - The Journal of Heart and …, 2017 - Elsevier
Background Ex vivo lung perfusion (EVLP) was primarily developed for evaluation of
impaired donor lungs. The good clinical results raise the question for its possible impact on …

Normothermic ex vivo lung perfusion in clinical lung transplantation

M Cypel, JC Yeung, M Liu, M Anraku… - New England journal …, 2011 - Mass Medical Soc
Background More than 80% of donor lungs are potentially injured and therefore not
considered suitable for transplantation. With the use of normothermic ex vivo lung perfusion …

Extension of donor lung preservation with hypothermic storage after normothermic ex vivo lung perfusion

MKY Hsin, I Iskender, D Nakajima, M Chen… - The Journal of Heart and …, 2016 - Elsevier
Background Ex vivo lung perfusion (EVLP) allows normothermic evaluation and treatment of
donor lungs not currently acceptable for transplant and improves organ use. Donor lungs …

The NOVEL study. A multi-center clinical trial studying the safety of ex vivo lung perfusion

PG Sanchez, E Cantu, M Hartwig, F D'Ovidio… - The Journal of Heart and …, 2020 - Elsevier
Purpose lung transplantation continues to be a life saving therapy for patients with end stage
lung disease. In a donor restrictive environment and with only 22% of donor lungs currently …

[引用][C] 173: Normothermic Human Ex Vivo Lung Perfusion (EVLP) for Improved Assessment of Extended Criteria Donor Lungs for Transplantation

M Cypel, J Yeung, M Liu, F Chen, W Karolak… - The Journal of Heart …, 2009 - jhltonline.org
Purpose Expected Completion Date: March 2009. Sponsor of the trial: VITROLIFE. Summary
of Objectives: 1) To examine the feasibility and safety of ex vivo perfusion of extended …

Three center experience with clinical normothermic ex vivo lung perfusion

M Cypel, C Aigner, E Sage, T Machuca… - The Journal of Heart …, 2013 - jhltonline.org
Purpose Normothermic ex vivo lung perfusion (EVLP) is a method to evaluate and improve
function of injured donor lungs. We reviewed 3-center experience using the previously …

Evaluating acellular versus cellular perfusate composition during prolonged ex vivo lung perfusion after initial cold ischaemia for 24 hours

S Becker, J Steinmeyer, M Avsar, K Höffler… - Transplant …, 2016 - Wiley Online Library
Normothermic ex vivo lung perfusion (EVLP) has developed as a powerful technique to
evaluate particularly marginal donor lungs prior to transplantation. In this study, acellular …

Normothermic ex vivo lung perfusion (novel) as an assessment of extended criteria donor lungs: a prospective multi-center clinical trial

PG Sanchez, EG Chan, RD Davis, M Hartwig… - The Journal of Heart …, 2022 - jhltonline.org
Purpose Ex vivo lung perfusion (EVLP) allows re-evaluation of extended criteria/marginal
donor lungs. This can increase the number of lung transplants. However, the long-term …