The interactive contributions of Na+/K+‐ATPase and nitric oxide synthase to sweating and cutaneous vasodilatation during exercise in the heat

JC Louie, N Fujii, RD Meade… - The Journal of …, 2016 - Wiley Online Library
Key points Nitric oxide synthase (NOS) contributes to sweating and cutaneous
vasodilatation during exercise in the heat. Similarly, reports show that Na+/K+‐ATPase …

Fluid replacement modulates oxidative stress-but not nitric oxide-mediated cutaneous vasodilation and sweating during prolonged exercise in the heat

BD McNeely, RD Meade, N Fujii… - American Journal …, 2017 - journals.physiology.org
The roles of nitric oxide synthase (NOS), reactive oxygen species (ROS), and angiotensin II
type 1 receptor (AT1R) activation in regulating cutaneous vasodilation and sweating during …

The roles of the Na+/K+‐ATPase, NKCC, and K+ channels in regulating local sweating and cutaneous blood flow during exercise in humans in vivo

JC Louie, N Fujii, RD Meade… - Physiological Reports, 2016 - Wiley Online Library
Abstract Na+/K+‐ATP ase has been shown to regulate the sweating and cutaneous vascular
responses during exercise; however, similar studies have not been conducted to assess the …

iNOS-dependent sweating and eNOS-dependent cutaneous vasodilation are evident in younger adults, but are diminished in older adults exercising in the heat

N Fujii, RD Meade, LM Alexander… - Journal of Applied …, 2016 - journals.physiology.org
Nitric oxide synthase (NOS) contributes to sweating and cutaneous vasodilation during
exercise in younger adults. We hypothesized that endothelial NOS (eNOS) and neuronal …

Type 1 diabetes modulates cyclooxygenase-and nitric oxide-dependent mechanisms governing sweating but not cutaneous vasodilation during exercise in the heat

N Fujii, S Dervis, RJ Sigal… - American Journal of …, 2016 - journals.physiology.org
Both cyclooxygenase (COX) and nitric oxide synthase (NOS) contribute to sweating,
whereas NOS alone contributes to cutaneous vasodilation during exercise in the heat. Here …

Endothelial nitric oxide synthase mediates the nitric oxide component of reflex cutaneous vasodilatation during dynamic exercise in humans

TC McNamara, JT Keen, GH Simmons… - The Journal of …, 2014 - Wiley Online Library
Key points Increases in skin blood flow and sweating also occur during exercise; however, it
is not known if the mechanisms controlling these responses are the same during passive …

Nonselective NOS inhibition blunts the sweat response to exercise in a warm environment

G Welch, KM Foote, C Hansen… - Journal of Applied …, 2009 - journals.physiology.org
The role of nitric oxide synthase (NOS) inhibition in modulating human thermoregulatory
control of sweating and cutaneous dilation was examined in 10 subjects (5 men and 5 …

Do nitric oxide synthase and cyclooxygenase contribute to the heat loss responses in older males exercising in the heat?

N Fujii, G Paull, RD Meade, R McGinn… - The Journal of …, 2015 - Wiley Online Library
Key points Studies show that nitric oxide synthase (NOS) and cyclooxygenase (COX) are
involved in sweating and cutaneous vascular regulation in young adults in a potentially …

Separate and combined effects of KCa and KATP channel blockade with NOS inhibition on cutaneous vasodilation and sweating in older men during heat stress

GW McGarr, N Fujii, CM Muia… - American Journal of …, 2019 - journals.physiology.org
Our objective in this study was to examine the separate and combined effects of potassium
(K+) channels and nitric oxide synthase (NOS) on cutaneous vasodilation and sweating in …

Oxidative stress does not influence local sweat rate during high‐intensity exercise

RD Meade, N Fujii, MP Poirier, P Boulay… - Experimental …, 2018 - Wiley Online Library
New Findings What is the central question of this study? We evaluated whether oxidative
stress attenuates the contribution of nitric oxide to sweating during high‐intensity exercise …