Persistent viral infection and its associated chronic diseases are a global health concern.
Interleukin (IL) 17–producing Th17 cells have been implicated in the pathogenesis of …

Th17 cells are recognized as indispensable in inducing protective immunity against bacteria
and fungi, as they promote the integrity of mucosal epithelial barriers. It is believed that Th17 …

The present review provides an overview of recent advances regarding the function of Th17
cells and their produced cytokines in the progression of viral diseases. Viral infections alone …

Our understanding of the role of T cells in human disease is undergoing revision as a result
of the discovery of T‐helper 17 (Th17) cells, a unique CD4+ T‐cell subset characterized by …

The view of CD4 T‐cell‐mediated immunity as a balance between distinct lineages of Th1
and Th2 cells has changed dramatically. Identification of the IL‐17 family of cytokines and of …

Th17 cells contribute to mucosal immunity by stimulating epithelial cells to induce
antimicrobial peptides, granulopoiesis, neutrophil recruitment, and tissue repair. Recent …

The role of Th17 lymphocytes in immunopathogenic processes has been well established,
but little is known about their basic cell features. In this study, we compared polarized Th1 …

Recently, a paradigm shift has emerged in T-cell-mediated adaptive immunity. On the heels
of the discovery of T cells with immunosuppressive function, so-called regulatory T cells …

Abstract T helper type 17 (Th17) cells are a distinct lineage of T cells that produce the
effector molecules IL-17, IL-17F, IL-21, and IL-22. Although the role of Th17 cells in primary …

IL-17-producing T cells (Th17) have been identified in mice as a distinct lineage of CD4+ T
helper cells. Since their discovery, efforts have been made in characterizing human Th17 …