[HTML][HTML] Pattern recognition receptors in health and diseases

D Li, M Wu - Signal transduction and targeted therapy, 2021 - nature.com
Pattern recognition receptors (PRRs) are a class of receptors that can directly recognize the
specific molecular structures on the surface of pathogens, apoptotic host cells, and damaged …

[HTML][HTML] Intracellular innate immune receptors: Life inside the cell

TD Kanneganti - Immunological reviews, 2020 - ncbi.nlm.nih.gov
The innate immune system is the critical first line of defense against infectious and sterile
insults. A cell's ability to sense these insults relies on a series of germline-encoded …

Identification and functions of pattern-recognition receptors

Y Kumagai, S Akira - Journal of Allergy and Clinical Immunology, 2010 - Elsevier
Since the identification of Toll-like receptors, our knowledge about pattern-recognition
receptors (PRRs) has increased rapidly. Classes of PRRs that have been recently …

[HTML][HTML] Toll-like receptors (TLRs), NOD-like receptors (NLRs), and RIG-I-like receptors (RLRs) in innate immunity. TLRs, NLRs, and RLRs ligands as …

K Wicherska-Pawłowska, T Wróbel… - International journal of …, 2021 - mdpi.com
The innate immune system plays a pivotal role in the first line of host defense against
infections and is equipped with patterns recognition receptors (PRRs) that recognize …

Toll‐like receptors: the swiss army knife of immunity and vaccine development

JK Dowling, A Mansell - Clinical & translational immunology, 2016 - Wiley Online Library
Innate immune cells have a critical role in defense against infection and disease. Central to
this is the broad specificity with which they can detect pathogen‐associated patterns and …

Therapeutic targeting of pattern-recognition receptors

N Rezaei - International immunopharmacology, 2006 - Elsevier
Innate immune system could recognize the pathogen-associated molecular patterns by
pattern-recognition receptors like Toll-like receptor (TLR) and nucleotide-binding …

Innate immunity: structure and function of TLRs

Y Delneste, C Beauvillain, P Jeannin - Medecine Sciences: M/S, 2007 - europepmc.org
The innate immune system provides the first line of defence against infection. Through a
limited number of germline-encoded receptors called pattern recognition receptors (PRRs) …

Pattern recognition receptors: sentinels in innate immunity and targets of new vaccine adjuvants

C Olive - Expert review of vaccines, 2012 - Taylor & Francis
The innate immune system plays an essential role in the host's first line of defense against
microbial invasion, and involves the recognition of distinct pathogen-associated molecular …

[HTML][HTML] Pattern recognition receptors: doubling up for the innate immune response

S Gordon - Cell, 2002 - cell.com
Antigen presenting cells (macrophages and dendritic cells) express pattern recognition
molecules that are thought to recognize foreign ligands during early phases of the immune …

Pathogen recognition and Toll-like receptor targeted therapeutics in innate immune cells

S Tartey, O Takeuchi - International reviews of immunology, 2017 - Taylor & Francis
The innate immune system deploys a variety of pattern-recognition receptors (PRRs) which
include Toll-like receptors (TLRs), RIG-I-like receptors, NOD-like receptors, and C-type lectin …