The endothelium is an established modulator of vascular tone; however, the recent
discovery of the anti‐contractile nature of perivascular adipose tissue (PVAT) suggests that …

Adipose tissue (AT) is an active endocrine organ with the ability to dynamically secrete a
wide range of adipocytokines. Importantly, its secretory profile is altered in various …

Perivascular adipose tissue (PVAT) is now recognized as an active player in vascular
homeostasis. The expansion of PVAT in obesity and its possible role in vascular dysfunction …

Adipose tissue is the largest endocrine organ, producing various adipokines and many other
substances. Almost all blood vessels are surrounded by perivascular adipose tissue (PVAT) …

Fat cells or adipocytes are distributed ubiquitously throughout the body and are often
regarded purely as energy stores. However, recently it has become clear that these …

Adipose tissue releases several hormones and autacoids and expansion of the adipose
tissue and excessive obesity is a risk factor for hypertension. Perivascular adipose tissue, on …

In addition to the endothelium, the perivascular adipose tissue (PVAT) has been described
to be involved in the local modulation of vascular function by synthetizing and releasing …

Perivascular adipose tissue (PVAT) is a specialized type of adipose tissue that surrounds
most mammalian blood vessels. PVAT is a metabolically active, endocrine organ capable of …

The heavy impact of obesity on the development and progression of cardiovascular disease
has sparked sustained efforts to uncover the mechanisms linking excess adiposity to …

Most blood vessels are surrounded by adipose tissue. Similarly to the adventitia,
perivascular adipose tissue (PVAT) was considered only as a passive structural support for …