[PDF][PDF] Strategies in the treatment of acute myeloid leukemia

B Lowenberg - Haematologica, 2004 - haematologica.org
The term acute myeloid leukemia (AML) collectively refers to a mixture of distinct diseases
that differ with regard to their pathogenetic evolution, genetic abnormalities, clinical features …

The past, present and future subclassification of patients with acute myeloid leukemia

RB Forthun, C Hinrichs, TH Dowling… - Current …, 2016 - ingentaconnect.com
Acute myeloid leukemia (AML) is characterized as a heterogeneous disease where the
patients are sub grouped according to several classification systems and mutational …

Therapy of acute myeloid leukemia: towards a patient-oriented, risk-adapted approach

F Mandelli, MC Petti, FL Coco - Haematologica, 1998 - haematologica.org
BACKGROUND AND OBJECTIVE: The successful use of differentiating treatment for
patients with acute promyelocytic leukemia (APL) suggests that other acute myeloid …

Towards a pathogenesis-oriented therapy of acute myeloid leukemia

W Hiddemann, K Spiekermann, C Buske… - Critical reviews in …, 2005 - Elsevier
Genetic and molecular techniques have provided increasing insights into the biology of
acute myeloid leukemia (AML). These investigations showed that AML is not a …

Molecular genetic pathways as therapeutic targets in acute myeloid leukemia

T Haferlach - ASH Education Program Book, 2008 - ashpublications.org
The heterogeneity of acute myeloid leukemia (AML) results from a complex network of
cytogenetic aberrations and molecular mutations. These genetic markers are the basis for …

Acute myeloid leukemia

FJ Giles, A Keating, AH Goldstone… - ASH Education …, 2002 - ashpublications.org
Abstract In this chapter, Drs. Keating and Willman review recent advances in our
understanding of the pathophysiology of acute myeloid leukemia (AML) and allied …

New strategies in acute myeloid leukemia: redefining prognostic markers to guide therapy

I Khan, JK Altman, JD Licht - Clinical Cancer Research, 2012 - AACR
Although standard therapy for AML has been relatively constant over the past 2 decades,
this may be changing with enhanced technologies allowing for the classification of acute …

New approaches in acute myeloid leukemia

W Blum, G Marcucci - Best Practice & Research Clinical Haematology, 2008 - Elsevier
Today, treatment of patients with acute myeloid leukemia (AML) remains predominantly a
“one-fits-all” approach with intensive cytarabine-based chemotherapy as the mainstay, but …

Gene expression profiling in acute myeloid leukemia

L Bullinger, PJM Valk - Journal of Clinical Oncology, 2005 - ascopubs.org
Over the last decades, significant advances have been made in the knowledge and
treatment of acute myeloid leukemia (AML). The WHO has recognized this new information …

Acute myeloid leukemia: biologic, prognostic, and therapeutic insights

S Khaled, M Al Malki, G Marcucci - Oncology, 2016 - go.gale.com
Acute myeloid leukemia (AML) is a biologically complex and molecularly and clinically
heterogeneous disease, and its incidence is increasing as the population ages …