[HTML][HTML] HLA-G Gene Variability Is Associated with Papillary Thyroid Carcinoma Morbidity and the HLA-G Protein Profile

BC Bertol, G Debortoli, FC Dias, JNG de Araújo… - International Journal of …, 2023 - mdpi.com
Human leukocyte antigen (HLA)-G is an immune checkpoint molecule that is highly
expressed in papillary thyroid carcinoma (PTC). The HLA-G gene presents several …

HLA‐G 3′ untranslated region polymorphic sites associated with increased HLA‐G production are more frequent in patients exhibiting differentiated thyroid tumours

NL de Figueiredo‐Feitosa… - Clinical …, 2017 - Wiley Online Library
Background HLA‐G is a nonclassical class I histocompatibility molecule implicated on the
immune escape mechanism of tumour cells. We evaluated the genetic diversity of HLA‐G …

Soluble human leukocyte antigen-g and its insertion/deletion polymorphism in papillary thyroid carcinoma: novel potential biomarkers of disease?

A Dardano, R Rizzo, A Polini, M Stignani… - The Journal of …, 2012 - academic.oup.com
Introduction: Human leukocyte antigen-G (HLA-G), a nonclassical major histocompatibility
complex class I antigen, plays a pivotal role in immune tolerance and a paradoxical role in …

Association between the HLA-G molecule and lymph node metastasis in papillary thyroid cancer

LM Nunes, FM Ayres, ICM Francescantonio… - Human immunology, 2013 - Elsevier
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer and can
present as lymph node metastasis in 30 to 65% of cases when initially diagnosed. High …

HLA-G is differentially expressed in thyroid tissues

NL de Figueiredo Feitosa, JCO Crispim, BR Zanetti… - Thyroid, 2014 - liebertpub.com
Background: HLA-G is a nonclassical major histocompatibility complex molecule that has
well-recognized immunomodulatory properties. The expression of HLA-G in tumor cells has …

[HTML][HTML] HLA-G 3'UTR polymorphism diplotypes and soluble HLA-G plasma levels impact cervical cancer susceptibility and prognosis

J Gan, XH Di, ZY Yan, YF Gao, HH Xu - Frontiers in Immunology, 2022 - frontiersin.org
Background Human leukocyte antigen G (HLA-G) is an immune checkpoint molecule with
relevance in several cancers. The aim of this study was to evaluate the potential role of …

[HTML][HTML] A critical assessment of the association between HLA-G expression by carcinomas and clinical outcome

RB van de Water, D Krijgsman, RD Houvast… - International Journal of …, 2021 - mdpi.com
Human leukocyte antigen-G (HLA-G) conveys immunological tolerance at the maternal-
foetal interface. HLA-G expression by tumour cells may also play such a role, resulting in …

Associations between HLA-C alleles and papillary thyroid carcinoma

V Haghpanah, K Khalooghi, K Adabi… - Cancer …, 2009 - content.iospress.com
Objective: Papillary thyroid carcinoma (PTC) is the most frequent types of thyroid
malignancies. Several genes may be involved in susceptibility of thyroid cancer including …

[HTML][HTML] Association of HLA-G 3′ UTR polymorphism and expression with the progression of cervical lesions in human papillomavirus 18 infections

HH Xu, X Zhang, HH Zheng, QY Han, AF Lin… - Infectious Agents and …, 2018 - Springer
Background Human leukocyte antigen (HLA)-G is an immune checkpoint molecule, which
expression in cervical cancer cells enables them to escape immunosurveillance. To date …

The relationship of 3′UTR HLA‐G14‐bp insertion/deletion and +3142 C/G polymorphisms and soluble HLA‐G expression with gynecological cancers: An updated …

K Tizaoui, M Jalouli, N Boujelbene… - Immunity …, 2022 - Wiley Online Library
Objectives Human leukocyte antigen‐G (HLA‐G) is implicated in several cancers and is
considered to be an immune checkpoint regulator. We determined the association between …