Correlates of protection against symptomatic and asymptomatic SARS-CoV-2 infection

S Feng, DJ Phillips, T White, H Sayal, PK Aley, S Bibi… - Nature medicine, 2021 - nature.com
The global supply of COVID-19 vaccines remains limited. An understanding of the immune
response that is predictive of protection could facilitate rapid licensure of new vaccines. Data …

Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses

JR Barrett, S Belij-Rammerstorfer, C Dold, KJ Ewer… - Nature medicine, 2021 - nature.com
More than 190 vaccines are currently in development to prevent infection by the novel
severe acute respiratory syndrome coronavirus 2. Animal studies suggest that while …

Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection

DS Khoury, D Cromer, A Reynaldi, TE Schlub… - Nature medicine, 2021 - nature.com
Predictive models of immune protection from COVID-19 are urgently needed to identify
correlates of protection to assist in the future deployment of vaccines. To address this, we …

In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains

RE Chen, ES Winkler, JB Case, ID Aziati, TL Bricker… - Nature, 2021 - nature.com
Rapidly emerging SARS-CoV-2 variants jeopardize antibody-based countermeasures.
Although cell culture experiments have demonstrated a loss of potency of several anti-spike …

When to update COVID-19 vaccine composition

R Grant, JA Sacks, P Abraham, S Chunsuttiwat… - Nature Medicine, 2023 - nature.com
When to update COVID-19 vaccine composition | Nature Medicine Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

Boosting immunity to COVID-19 vaccines

JA Juno, AK Wheatley - Nature medicine, 2021 - nature.com
Boosting immunity to COVID-19 vaccines | Nature Medicine Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain the …

Impact of vaccination on new SARS-CoV-2 infections in the United Kingdom

E Pritchard, PC Matthews, N Stoesser, DW Eyre… - Nature medicine, 2021 - nature.com
The effectiveness of COVID-19 vaccination in preventing new severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infections in the general community is still unclear …

Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies

RE Chen, X Zhang, JB Case, ES Winkler, Y Liu… - Nature medicine, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the global
COVID-19 pandemic. Rapidly spreading SARS-CoV-2 variants may jeopardize newly …

A correlate of protection for SARS-CoV-2 vaccines is urgently needed

F Krammer - Nature medicine, 2021 - nature.com
A correlate of protection for SARS-CoV-2 vaccines is urgently needed | Nature Medicine Skip to
main content Thank you for visiting nature.com. You are using a browser version with limited …

Preliminary analysis of safety and immunogenicity of a SARS-CoV-2 variant vaccine booster

K Wu, A Choi, M Koch, LZ Ma, A Hill, N Nunna… - MedRxiv, 2021 - medrxiv.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of a
global pandemic of coronavirus disease 2019 (COVID-19) that has led to more than 3 …