Plasma biomarkers predict Alzheimer's disease before clinical onset in Chinese cohorts
H Cai, Y Pang, X Fu, Z Ren, L Jia - Nature Communications, 2023 - nature.com
Plasma amyloid-β (Aβ) 42, phosphorylated tau (p-tau) 181, and neurofilament light chain
(NfL) are promising biomarkers of Alzheimer's disease (AD). However, whether these …
(NfL) are promising biomarkers of Alzheimer's disease (AD). However, whether these …
Longitudinal blood biomarker trajectories in preclinical Alzheimer's disease
Y Yakoub, NJ Ashton… - Alzheimer's & …, 2023 - Wiley Online Library
INTRODUCTION Plasma biomarkers are altered years prior to Alzheimer's disease (AD)
clinical onset. METHODS We measured longitudinal changes in plasma amyloid‐beta (Aβ) …
clinical onset. METHODS We measured longitudinal changes in plasma amyloid‐beta (Aβ) …
Plasma p‐tau181, p‐tau217, and other blood‐based Alzheimer's disease biomarkers in a multi‐ethnic, community study
Abstract Introduction Blood‐based Alzheimer's disease (AD) biomarkers provide
opportunities for community studies and across ethnic groups. We investigated blood …
opportunities for community studies and across ethnic groups. We investigated blood …
Plasma Aβ42/Aβ40 and p-tau181 predict long-term clinical progression in a cohort with amnestic mild cognitive impairment
Z Xiao, W Wu, X Ma, X Liang, J Lu, L Zheng… - Clinical …, 2022 - academic.oup.com
Background Previous studies reported the value of blood-based biomarkers in predicting
Alzheimer disease (AD) progression among individuals with different disease stages …
Alzheimer disease (AD) progression among individuals with different disease stages …
Detecting amyloid positivity in early Alzheimer's disease using combinations of plasma Aβ42/Aβ40 and p‐tau
S Janelidze, S Palmqvist, A Leuzy… - Alzheimer's & …, 2022 - Wiley Online Library
Introduction We studied usefulness of combining blood amyloid beta (Aβ) 42/Aβ40,
phosphorylated tau (p‐tau) 217, and neurofilament light (NfL) to detect abnormal brain Aβ …
phosphorylated tau (p‐tau) 217, and neurofilament light (NfL) to detect abnormal brain Aβ …
Plasma Aβ42/40 ratio, p‐tau181, GFAP, and NfL across the Alzheimer's disease continuum: a cross‐sectional and longitudinal study in the AIBL cohort
Introduction Plasma amyloid beta (Aβ) 1‐42/Aβ1‐40 ratio, phosphorylated‐tau181 (p‐
tau181), glial fibrillary acidic protein (GFAP), and neurofilament light (NfL) are putative blood …
tau181), glial fibrillary acidic protein (GFAP), and neurofilament light (NfL) are putative blood …
Associations of plasma phosphorylated tau181 and neurofilament light chain with brain amyloid burden and cognition in objectively defined subtle cognitive decline …
Y Huang, Y Li, F Xie, Q Guo - CNS Neuroscience & …, 2022 - Wiley Online Library
Aims There is increasing evidence that plasma biomarkers are specific biomarkers for
Alzheimer's disease (AD) pathology, but their potential utility in Obj‐SCD (objectively …
Alzheimer's disease (AD) pathology, but their potential utility in Obj‐SCD (objectively …
Plasma p-tau181 level predicts neurodegeneration and progression to Alzheimer's dementia: a longitudinal study
YL Wang, J Chen, ZL Du, H Weng, Y Zhang… - Frontiers in …, 2021 - frontiersin.org
Background: Plasma-based biomarkers would be potential biomarkers for early diagnosis of
Alzheimer's disease (AD) because they are more available and cost-effective than …
Alzheimer's disease (AD) because they are more available and cost-effective than …
Plasma biomarkers identify older adults at risk of Alzheimer's disease and related dementias in a real‐world population‐based cohort
PCL Ferreira, Y Zhang, B Snitz… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction Plasma biomarkers—cost effective, non‐invasive indicators of Alzheimer's
disease (AD) and related disorders (ADRD)—have largely been studied in clinical research …
disease (AD) and related disorders (ADRD)—have largely been studied in clinical research …
Specific associations between plasma biomarkers and postmortem amyloid plaque and tau tangle loads
Several promising plasma biomarkers for Alzheimer's disease have been recently
developed, but their neuropathological correlates have not yet been fully determined. To …
developed, but their neuropathological correlates have not yet been fully determined. To …
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