Paternal cigarette smoke (CS) exposure is associated with increased risk of behavioral
disorders and cancer in offspring, but the mechanism has not been identified. Here we use …

Converging evidence suggests that parental exposure to drugs of abuse can affect offspring
phenotypes. The impacts of drug abuse on germ cell quality may mediate multigenerational …

Cigarette smoke (CS) imposes a strong oxidative burden on exposed tissues resulting in a
severely disturbed oxidant/antioxidant balance, which in the context of chronic exposure is …

Background Maternal smoking of traditional or electronic cigarettes during pregnancy, which
constitutes developmental nicotine exposure (DNE), heightens the risk of …

Use of tobacco products is injurious to health in men and women. However, tobacco use by
pregnant women receives greater scrutiny because it can also compromise the health of …

Multigenerational inheritance is a nongenomic form of heritability characterized by altered
phenotypes in the first generation born from the exposed parent. Multigenerational factors …

Chronic Obstructive Pulmonary Disease (COPD) is a highly prevalent condition
characterized by inflammation and progressive obstruction of the airways. At present, there …

Background Experimental studies suggest that exposures may impact respiratory health
across generations via epigenetic changes transmitted specifically through male germ cells …

Active cigarette smoking increases oxidative damage, DNA adducts, DNA strand breaks,
chromosomal aberrations, and heritable mutations in sperm. However, little is known …

Background Although paternal exposure to cigarette smoke may contribute to obesity and
metabolic syndrome in offspring, the underlying mechanisms remain uncertain. Methods In …