Despite immense progress in our ability to prevent and treat HIV-1 infection, HIV-1 remains
an incurable disease and a highly efficacious HIV-1 vaccine is not yet available. Additional …

Broadly neutralizing antibodies (bNAbs) have been evaluated as promising agents in the
fight against infectious diseases. HIV-1-specific bNAbs, in particular, have been tested in …

In this Review, we highlight some recent developments in the discovery and application of
broadly neutralizing antibodies (bnAbs) to human immunodeficiency virus (HIV); ie …

Highlights•Broadly neutralizing antibodies are promising for HIV-1 prevention and
therapy.•Newly identified bNAbs reveal novel epitopes and binding modes.•Effective …

Encouraging results from preclinical and clinical studies support the development of bNAbs
for prevention and a number of antibodies with exceptional breadth and potency are …

Summary bNAbs may offer advantages over traditional ART for both the prevention and
treatment of HIV-1 infection. In addition, bNAbs may target the latent viral reservoir. bNAb …

Broadly neutralizing antibodies for treatment and prevention... : Current Opinion in HIV and
AIDS Broadly neutralizing antibodies for treatment and prevention of HIV-1 infection : Current …

Introduction: The currently available anti-HIV-1 drugs can control the infection but do not
eradicate the virus. Their long-term use can lead to side effects and resistance to therapy …

Early clinical studies support additional evaluation of bNAbs. Antibodies may offer
advantages over standard ART for HIV-1 prevention and therapy, and as components of …

Antibodies that naturally develop in some individuals infected with human immunodeficiency
virus 1 (HIV-1) and are capable of broadly neutralizing diverse strains of HIV-1 are useful for …