Multi-omics strategies are indispensable tools in the search for new anti-tuberculosis drugs.
Omics methodologies, where the ensemble of a class of biological molecules are measured …

Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium
tuberculosis. According to the WHO, the disease is one of the top 10 causes of death of …

The tuberculosis (TB) drug discovery pipeline is fueled by compounds identified in whole-
cell screens against the causative agent, Mycobacterium tuberculosis. Phenotypic screening …

Whole cell-based phenotypic screens have become the primary mode of hit generation in
tuberculosis (TB) drug discovery during the last two decades. Different drug screening …

Conspectus Tuberculosis (TB) is the leading cause of mortality globally resulting from an
infectious disease, killing almost 1.6 million people annually and accounting for …

We are witnessing the growing menace of both increasing cases of drug-sensitive and drug-
resistant Mycobacterium tuberculosis strains and the challenge to produce the first new …

New drugs that retain potency against multidrug/extensively drug-resistant strains of
Mycobacterium tuberculosis, with the additional benefit of a shortened treatment duration …

The use of chemical techniques to study biological systems (often referred to currently as
chemical biology) has become a powerful tool for both drug discovery and the development …

Once considered a crowning achievement of modern drug development, tuberculosis (TB)
chemotherapy has proven increasingly unable to keep pace with the spread of the …

An organism requires a range of biomolecules for its growth. By definition, these are
essential molecules which constitute the basic metabolic requirements of an organism. A …