[HTML][HTML] Exploring the mechanisms behind long noncoding RNAs and cancer

MM Balas, AM Johnson - Non-coding RNA research, 2018 - Elsevier
Over the past decade, long noncoding RNAs (lncRNAs) have been identified as significant
players in gene regulation. They are often differentially expressed and widely-associated …

A mechanistic view of long noncoding RNAs in cancer

L Winkler, N Dimitrova - Wiley Interdisciplinary Reviews: RNA, 2022 - Wiley Online Library
Long noncoding RNAs (lncRNAs) have emerged as important modulators of a wide range of
biological processes in normal and disease states. In particular, lncRNAs have garnered …

Long noncoding RNAs in cancer and therapeutic potential

A Renganathan, E Felley-Bosco - Long Non Coding RNA Biology, 2017 - Springer
Long noncoding RNAs (lncRNAs) are the major elements of the mammalian transcriptome
that is emerging as a central player controlling diverse cellular mechanisms. Most of the well …

Long noncoding RNAs in cancer: mechanisms of action and technological advancements

N Bartonicek, JLV Maag, ME Dinger - Molecular cancer, 2016 - Springer
The previous decade has seen long non-coding RNAs (lncRNAs) rise from obscurity to
being defined as a category of genetic elements, leaving its mark on the field of cancer …

[HTML][HTML] Post-transcriptional regulation of long noncoding RNAs in cancer

X Shi, M Sun, Y Wu, Y Yao, H Liu, G Wu, D Yuan… - Tumor Biology, 2015 - Springer
It is a great surprise that the genomes of mammals and other eukaryotes harbor many
thousands of long noncoding RNAs (lncRNAs). Although these long noncoding transcripts …

Long noncoding RNAs in cancer: from discovery to therapeutic targets

R Choudhari, MJ Sedano, AL Harrison… - Advances in clinical …, 2020 - Elsevier
Long noncoding RNAs (lncRNAs) have recently gained considerable attention as key
players in biological regulation; however, the mechanisms by which lncRNAs govern …

Perspectives of long non-coding RNAs in cancer

AKDM Rao, T Rajkumar, S Mani - Molecular biology reports, 2017 - Springer
A recent advance in transcriptomics has spawned the 'Decade of non-coding RNAs' by
potentiating the growing numbers of long non-coding RNA in cancer. LncRNA involvement …

Long noncoding RNAs in cancer: from function to translation

A Sahu, U Singhal, AM Chinnaiyan - Trends in cancer, 2015 - cell.com
While our understanding of the molecular mechanisms underlying cancer has significantly
improved, most of our knowledge focuses on protein-coding genes that make up a fraction of …

The functional role of long non-coding RNA in human carcinomas

EA Gibb, CJ Brown, WL Lam - Molecular cancer, 2011 - Springer
Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm
demonstrating potential roles in both oncogenic and tumor suppressive pathways. These …

[HTML][HTML] Long noncoding RNAs and their link to cancer

JM Grixti, D Ayers - Non-coding RNA research, 2020 - Elsevier
The central dogma of molecular biology, developed from the study of simple organisms such
as Escherichia coli, has up until recently been that RNA functions mainly as an information …