Observation of intramyocellular lipids by means of 1H magnetic resonance spectroscopy

C Boesch, J Décombaz, J Slotboom… - Proceedings of the …, 1999 - cambridge.org
Magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) are being
increasingly used for investigations of human muscle physiology. While MRI reveals the …

Standardized protocol for a depletion of intramyocellular lipids (IMCL)

M Ith, PM Huber, A Egger, JP Schmid… - NMR in …, 2010 - Wiley Online Library
Intramyocellular lipids (IMCL) are flexible fuel stores that are depleted by physical exercise
and replenished by fat intake. IMCL or their degradation products are thought to interfere …

Observation of Intramyocellular Lipids by1H‐Magnetic Resonance Spectroscopy

C Boesch, R Kreis - Annals of the New York Academy of …, 2000 - Wiley Online Library
Magnetic resonance (MR) methods are increasingly being used to investigate the
physiology of human muscle. Although MR imaging (MRI) reveals the morphology of …

Skeletal muscle 1H MRSI before and after prolonged exercise. I. muscle specific depletion of intramyocellular lipids

P Vermathen, P Saillen, A Boss… - Magnetic resonance …, 2012 - Wiley Online Library
Aim of the study was to determine distribution and depletion patterns of intramyocellular
lipids (IMCL) in leg muscles before and after two types of standardized endurance exercise …

Effect of diet on the replenishment of intramyocellular lipids after exercise

J Decombaz, M Fleith, H Hoppeler, R Kreis… - European journal of …, 2000 - Springer
Background Muscle triglycerides are important as a source of energy and in relation to
metabolic sensitivity. However, the classic biopsy method does not distinguish intra-from …

Role of proton MR for the study of muscle lipid metabolism

C Boesch, J Machann, P Vermathen… - NMR in Biomedicine …, 2006 - Wiley Online Library
Abstract 1H‐MR spectroscopy (MRS) of intramyocellular lipids (IMCL) became particularly
important when it was recognized that IMCL levels are related to insulin sensitivity. While …

In vivo determination of intra‐myocellular lipids in human muscle by means of localized 1H‐MR‐spectroscopy

C Boesch, J Slotboom, H Hoppeler… - Magnetic resonance in …, 1997 - Wiley Online Library
Intra‐myocellular lipids (IMCL) are stored in droplets in the cytoplasm of muscle cells and
are an energy storage form readily accessed during long‐term exercise. 1H‐MR …

Utilisation of intramyocellular lipids (IMCLs) during exercise as assessed by proton magnetic resonance spectroscopy (1H-MRS)

K Brechtel, AM Niess, J Machann, K Rett… - Hormone and …, 2001 - thieme-connect.com
Trained subjects are characterized by enhanced levels of lipolytic and mitochondrial
enzymes, and, hence, a higher reliance on fat oxidation, especially during aerobic …

Content of intramyocellular lipids derived by electron microscopy, biochemical assays, and 1H-MR spectroscopy

H Howald, C Boesch, R Kreis… - Journal of Applied …, 2002 - journals.physiology.org
Three different methods to determine intramyocellular lipid (IMCL) contents in human
skeletal muscle have been compared. 1H-magnetic resonance spectroscopy (MRS) was …

Determinants of intramyocellular lipid concentrations in rat hindleg muscle

C Neumann‐Haefelin, J Kuhlmann… - … in Medicine: An …, 2003 - Wiley Online Library
The investigation of intramyocellular lipids (IMCLs) with proton MR spectroscopy (1H‐MRS)
in humans has recently received increasing attention. IMCL levels correlate with insulin …