Biomaterials and tissue engineering approaches using glycosaminoglycans for tissue repair: Lessons learned from the native extracellular matrix

R Menezes, R Vincent, L Osorno, P Hu, TL Arinzeh - Acta biomaterialia, 2023 - Elsevier
Glycosaminoglycans (GAGs) are an important component of the extracellular matrix as they
influence cell behavior and have been sought for tissue regeneration, biomaterials, and …

Medical application of glycosaminoglycans: a review

A Köwitsch, G Zhou, T Groth - Journal of tissue engineering …, 2018 - Wiley Online Library
The characteristic molecular composition of the different glycosaminoglycans (GAGs) is
related to their role as structural components and regulators of a multitude of functions of …

Glycosaminoglycan derivatives: promising candidates for the design of functional biomaterials

D Scharnweber, L Hübner, S Rother, U Hempel… - Journal of Materials …, 2015 - Springer
Numerous biological processes (tissue formation, remodelling and healing) are strongly
influenced by the cellular microenvironment. Glycosaminoglycans (GAGs) are important …

Glycosaminoglycans' ability to promote wound healing: from native living macromolecules to artificial Biomaterials

P Yang, Y Lu, W Gou, Y Qin, J Tan, G Luo… - Advanced …, 2024 - Wiley Online Library
Glycosaminoglycans (GAGs) are important for the occurrence of signaling molecules and
maintenance of microenvironment within the extracellular matrix (ECM) in living tissues …

[HTML][HTML] Glycosaminoglycan-inspired biomaterials for the development of bioactive hydrogel networks

MI Neves, M Araujo, L Moroni, RMP da Silva… - Molecules, 2020 - mdpi.com
Glycosaminoglycans (GAG) are long, linear polysaccharides that display a wide range of
relevant biological roles. Particularly, in the extracellular matrix (ECM) GAG specifically …

Glycosaminoglycan and proteoglycan‐based biomaterials: current trends and future perspectives

J Rnjak‐Kovacina, F Tang… - Advanced healthcare …, 2018 - Wiley Online Library
Proteoglycans and their glycosaminoglycans (GAG) are essential for life as they are
responsible for orchestrating many essential functions in development and tissue …

[HTML][HTML] Glycosaminoglycans in tissue engineering: a review

H Sodhi, A Panitch - Biomolecules, 2020 - mdpi.com
Glycosaminoglycans are native components of the extracellular matrix that drive cell
behavior and control the microenvironment surrounding cells, making them promising …

Compositional and structural analysis of glycosaminoglycans in cell-derived extracellular matrices

JC Silva, MS Carvalho, X Han, K Xia, PE Mikael… - Glycoconjugate …, 2019 - Springer
The extracellular matrix (ECM) is a highly dynamic and complex meshwork of proteins and
glycosaminoglycans (GAGs) with a crucial role in tissue homeostasis and organization not …

Neoproteoglycans in tissue engineering

A Weyers, RJ Linhardt - The FEBS journal, 2013 - Wiley Online Library
Proteoglycans, comprised of a core protein to which glycosaminoglycan chains are
covalently linked, are an important structural and functional family of macromolecules found …

Naturally derived proteins and glycosaminoglycan scaffolds for tissue engineering applications

N Celikkin, C Rinoldi, M Costantini, M Trombetta… - Materials Science and …, 2017 - Elsevier
Tissue engineering (TE) aims to mimic the complex environment where organogenesis
takes place using advanced materials to recapitulate the tissue niche. Cells, three …