[HTML][HTML] Major scientific hurdles in HIV vaccine development: historical perspective and future directions
T Ng'uni, C Chasara, ZM Ndhlovu - Frontiers in immunology, 2020 - frontiersin.org
Following the discovery of HIV as a causative agent of AIDS, the expectation was to rapidly
develop a vaccine; but thirty years later, we still do not have a licensed vaccine. Progress …
develop a vaccine; but thirty years later, we still do not have a licensed vaccine. Progress …
[HTML][HTML] Advancing an HIV vaccine; advancing vaccinology
DR Burton - Nature Reviews Immunology, 2019 - nature.com
Of any pathogen, HIV provides perhaps the greatest challenge to successful vaccine
development. Nevertheless, progress continued to be made in 2018; new vaccine concepts …
development. Nevertheless, progress continued to be made in 2018; new vaccine concepts …
HIV-1 vaccine development after STEP
DH Barouch, B Korber - Annual review of medicine, 2010 - annualreviews.org
Despite more than 25 years of concerted worldwide research, the development of a safe and
effective HIV-1 vaccine remains elusive. Prototype antibody-based and T cell–based HIV-1 …
effective HIV-1 vaccine remains elusive. Prototype antibody-based and T cell–based HIV-1 …
[HTML][HTML] Advances in HIV-1 vaccine development
An efficacious HIV-1 vaccine is regarded as the best way to halt the ongoing HIV-1
epidemic. However, despite significant efforts to develop a safe and effective vaccine, the …
epidemic. However, despite significant efforts to develop a safe and effective vaccine, the …
Current approaches to HIV vaccine development: a narrative review
Introduction The development of an effective vaccine to protect against HIV is a longstanding
global health need complicated by challenges inherent to HIV biology and to the execution …
global health need complicated by challenges inherent to HIV biology and to the execution …
[HTML][HTML] Challenges in HIV vaccine research for treatment and prevention
B Ensoli, A Cafaro, P Monini, S Marcotullio… - Frontiers in …, 2014 - frontiersin.org
Many attempts have been made or are ongoing for HIV prevention and HIV cure. Many
successes are in the list, particularly for HIV drugs, recently proposed also for prevention …
successes are in the list, particularly for HIV drugs, recently proposed also for prevention …
Progress in HIV-1 vaccine development
BF Haynes, MA Moody, M Alam, M Bonsignori… - Journal of Allergy and …, 2014 - Elsevier
The past 2 years have seen a number of basic and translational science advances in the
quest for development of an effective HIV-1 vaccine. These advances include discovery of …
quest for development of an effective HIV-1 vaccine. These advances include discovery of …
Human immunodeficiency virus (HIV) immunopathogenesis and vaccine development: a review
MP Girard, S Osmanov, OM Assossou, MP Kieny - Vaccine, 2011 - Elsevier
The development of a safe, effective and globally affordable HIV vaccine offers the best
hope for the future control of the HIV-1 pandemic. Since 1987, scores of candidate HIV-1 …
hope for the future control of the HIV-1 pandemic. Since 1987, scores of candidate HIV-1 …
New paradigms for HIV/AIDS vaccine development
LJ Picker, SG Hansen, JD Lifson - Annual review of medicine, 2012 - annualreviews.org
HIV-1 and its simian counterpart SIV have been exquisitely tailored by evolution to evade
host immunity. By virtue of specific adaptations that thwart individual innate or adaptive …
host immunity. By virtue of specific adaptations that thwart individual innate or adaptive …