Growth factor delivery: Defining the next generation platforms for tissue engineering

LMC Aguilar, SM Silva, SE Moulton - Journal of controlled Release, 2019 - Elsevier
Growth factors play a crucial role in tissue engineering by directing the fate of cells and
allowing the formation of tissues. Understanding the key requirements for growth factor …

Growth factor delivery-based tissue engineering: general approaches and a review of recent developments

K Lee, EA Silva, DJ Mooney - Journal of the Royal …, 2011 - royalsocietypublishing.org
The identification and production of recombinant morphogens and growth factors that play
key roles in tissue regeneration have generated much enthusiasm and numerous clinical …

Engineering growth factors for regenerative medicine applications

AC Mitchell, PS Briquez, JA Hubbell, JR Cochran - Acta biomaterialia, 2016 - Elsevier
Growth factors are important morphogenetic proteins that instruct cell behavior and guide
tissue repair and renewal. Although their therapeutic potential holds great promise in …

Controlled growth factor delivery for tissue engineering

P Tayalia, DJ Mooney - Advanced materials, 2009 - Wiley Online Library
Growth factors play a crucial role in information transfer between cells and their
microenvironment in tissue engineering and regeneration. They initiate their action by …

Growth factor engineering strategies for regenerative medicine applications

X Ren, M Zhao, B Lash, MM Martino… - … in bioengineering and …, 2020 - frontiersin.org
Growth factors are critical molecules for tissue repair and regeneration. Therefore,
recombinant growth factors have raised a lot of hope for regenerative medicine applications …

Growth factor-delivery systems for tissue engineering: a materials perspective

R Vasita, DS Katti - Expert review of medical devices, 2006 - Taylor & Francis
The transplantation of organs, their surgical reconstruction or implantation of synthetic
devices that can perform the function of organs, are the currently available methods for …

Materials science and design principles of growth factor delivery systems in tissue engineering and regenerative medicine

R Subbiah, RE Guldberg - Advanced healthcare materials, 2019 - Wiley Online Library
Growth factors (GFs) are signaling molecules that direct cell development by providing
biochemical cues for stem cell proliferation, migration, and differentiation. GFs play a key …

Growth factor release from tissue engineering scaffolds

MJ Whitaker, RA Quirk, SM Howdle… - Journal of Pharmacy …, 2001 - Wiley Online Library
Synthetic scaffold materials are used in tissue engineering for a variety of applications,
including physical supports for the creation of functional tissues, protective gels to aid in …

Growth factor delivery approaches in hydrogels

AKA Silva, C Richard, M Bessodes… - …, 2009 - ACS Publications
The controlled delivery of growth factors is a very challenging task because many different
issues have to be addressed to develop the best suited system. A wide range of approaches …

Toward delivery of multiple growth factors in tissue engineering

FM Chen, M Zhang, ZF Wu - Biomaterials, 2010 - Elsevier
Inspired by physiological events that accompany the “wound healing cascade”, the concept
of developing a tissue either in vitro or in vivo has led to the integration of a wide variety of …