Peripheral and lung resident memory T cell responses against SARS-CoV-2
J Grau-Expósito, N Sánchez-Gaona, N Massana… - Nature …, 2021 - nature.com
Resident memory T cells (TRM) positioned within the respiratory tract are probably required
to limit SARS-CoV-2 spread and COVID-19. Importantly, TRM are mostly non-recirculating …
to limit SARS-CoV-2 spread and COVID-19. Importantly, TRM are mostly non-recirculating …
SARS-CoV-2-specific T cell memory is sustained in COVID-19 convalescent patients for 10 months with successful development of stem cell-like memory T cells
JH Jung, MS Rha, M Sa, HK Choi, JH Jeon… - Nature …, 2021 - nature.com
Memory T cells contribute to rapid viral clearance during re-infection, but the longevity and
differentiation of SARS-CoV-2-specific memory T cells remain unclear. Here we conduct ex …
differentiation of SARS-CoV-2-specific memory T cells remain unclear. Here we conduct ex …
Limited induction of polyfunctional lung-resident memory T cells against SARS-CoV-2 by mRNA vaccination compared to infection
DKJ Pieren, SG Kuguel, J Rosado, AG Robles… - Nature …, 2023 - nature.com
Resident memory T cells (TRM) present at the respiratory tract may be essential to enhance
early SARS-CoV-2 viral clearance, thus limiting viral infection and disease. While long-term …
early SARS-CoV-2 viral clearance, thus limiting viral infection and disease. While long-term …
Unique properties of tissue-resident memory T cells in the lungs: implications for COVID-19 and other respiratory diseases
FR Carbone - Nature Reviews Immunology, 2023 - nature.com
Tissue-resident memory T (TRM) cells were originally identified as a tissue-sequestered
population of memory T cells that show lifelong persistence in non-lymphoid organs. That …
population of memory T cells that show lifelong persistence in non-lymphoid organs. That …
Exposure to SARS-CoV-2 generates T-cell memory in the absence of a detectable viral infection
T-cell immunity is important for recovery from COVID-19 and provides heightened immunity
for re-infection. However, little is known about the SARS-CoV-2-specific T-cell immunity in …
for re-infection. However, little is known about the SARS-CoV-2-specific T-cell immunity in …
SARS-CoV-2 infection generates tissue-localized immunological memory in humans
Adaptive immune responses to SARS-CoV-2 infection have been extensively characterized
in blood; however, most functions of protective immunity must be accomplished in tissues …
in blood; however, most functions of protective immunity must be accomplished in tissues …
[PDF][PDF] Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19
T Sekine, A Perez-Potti, O Rivera-Ballesteros, K Strålin… - Cell, 2020 - cell.com
Summary SARS-CoV-2-specific memory T cells will likely prove critical for long-term immune
protection against COVID-19. Here, we systematically mapped the functional and …
protection against COVID-19. Here, we systematically mapped the functional and …
[PDF][PDF] T cell memory: understanding COVID-19
NN Jarjour, D Masopust, SC Jameson - Immunity, 2021 - cell.com
As the SARS-CoV-2 pandemic has progressed, increasing attention has focused on
establishing natural and vaccine-induced immunity against this coronavirus and the …
establishing natural and vaccine-induced immunity against this coronavirus and the …
Identification of resident memory CD8+ T cells with functional specificity for SARS-CoV-2 in unexposed oropharyngeal lymphoid tissue
Cross-reactive CD4+ T cells that recognize severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) are more commonly detected in the peripheral blood of unexposed …
(SARS-CoV-2) are more commonly detected in the peripheral blood of unexposed …
Tissue‐resident memory T cells and lung immunopathology
IS Cheon, YM Son, J Sun - Immunological Reviews, 2023 - Wiley Online Library
Rapid reaction to microbes invading mucosal tissues is key to protect the host against
disease. Respiratory tissue‐resident memory T (TRM) cells provide superior immunity …
disease. Respiratory tissue‐resident memory T (TRM) cells provide superior immunity …
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