[HTML][HTML] Role of uremic toxins in early vascular ageing and calcification

NC Kyriakidis, G Cobo, L Dai, B Lindholm, P Stenvinkel - Toxins, 2021 - mdpi.com
In patients with advanced chronic kidney disease (CKD), the accumulation of uremic toxins,
caused by a combination of decreased excretion secondary to reduced kidney function and …

[HTML][HTML] Uremic toxins and vascular calcification–missing the forest for all the trees

N Rapp, P Evenepoel, P Stenvinkel, L Schurgers - Toxins, 2020 - mdpi.com
The cardiorenal syndrome relates to the detrimental interplay between the vascular system
and the kidney. The uremic milieu induced by reduced kidney function alters the phenotype …

[HTML][HTML] The impact of uremic toxins on vascular smooth muscle cell function

L Hénaut, A Mary, JM Chillon, S Kamel, ZA Massy - Toxins, 2018 - mdpi.com
Chronic kidney disease (CKD) is associated with profound vascular remodeling, which
accelerates the progression of cardiovascular disease. This remodeling is characterized by …

[HTML][HTML] Uremic toxins affecting cardiovascular calcification: a systematic review

J Holmar, S de la Puente-Secades, J Floege, H Noels… - Cells, 2020 - mdpi.com
Cardiovascular calcification is highly prevalent and associated with increased morbidity in
chronic kidney disease (CKD). This review examines the impact of uremic toxins, which …

[HTML][HTML] Uremic vascular calcification: the pathogenic roles and gastrointestinal decontamination of uremic toxins

CT Chao, SH Lin - Toxins, 2020 - mdpi.com
Uremic vascular calcification (VC) commonly occurs during advanced chronic kidney
disease (CKD) and significantly increases cardiovascular morbidity and mortality. Uremic …

[HTML][HTML] Uremic toxins in the progression of chronic kidney disease and cardiovascular disease: mechanisms and therapeutic targets

YJ Lim, NA Sidor, NC Tonial, A Che, BL Urquhart - Toxins, 2021 - mdpi.com
Chronic kidney disease (CKD) is a progressive loss of renal function. The gradual decline in
kidney function leads to an accumulation of toxins normally cleared by the kidneys, resulting …

[HTML][HTML] Impact of uremic toxins on endothelial dysfunction in chronic kidney disease: a systematic review

E Harlacher, J Wollenhaupt, CC Baaten… - International journal of …, 2022 - mdpi.com
Patients with chronic kidney disease (CKD) are at a highly increased risk of cardiovascular
complications, with increased vascular inflammation, accelerated atherogenesis and …

[HTML][HTML] Effects of chronic kidney disease and uremic toxins on extracellular vesicle biology

L Yaker, S Kamel, J Ausseil, A Boullier - Toxins, 2020 - mdpi.com
Vascular calcification (VC) is a cardiovascular complication associated with a high mortality
rate, especially in patients with diabetes, atherosclerosis or chronic kidney disease (CKD). In …

[HTML][HTML] Uremic toxins and vascular dysfunction

I Six, N Flissi, G Lenglet, L Louvet, S Kamel, M Gallet… - Toxins, 2020 - mdpi.com
Vascular dysfunction is an essential element found in many cardiovascular pathologies and
in pathologies that have a cardiovascular impact such as chronic kidney disease (CKD) …

Uremic toxin–targeting as a therapeutic strategy for preventing cardiorenal syndrome

K Taguchi, BC Elias, CR Brooks, S Ueda… - Circulation …, 2019 - jstage.jst.go.jp
Chronic kidney disease (CKD) is a global health problem. CKD patients are at high risk of
developing cardiovascular disease (CVD), including coronary artery disease, heart failure …